Powder: -20°C for 3 years | In solvent: -80°C for 1 year
21-Deoxycortisol is a corticosteroid metabolite of 17-hydroxyprogesterone produced in the adrenal glandvia11-hydroxylation by 11β-hydroxylase.1,2Serum levels of 21-deoxycortisol are elevated in patients with congenital adrenal hyperplasia that are heterozygous for mutations inCYP2A21, the gene encoding steroid 21-hydroxylase, and have been used as a biomarker for the detection of 21-hydroxylase deficiencies.
Description | 21-Deoxycortisol is a corticosteroid metabolite of 17-hydroxyprogesterone produced in the adrenal glandvia11-hydroxylation by 11β-hydroxylase.1,2Serum levels of 21-deoxycortisol are elevated in patients with congenital adrenal hyperplasia that are heterozygous for mutations inCYP2A21, the gene encoding steroid 21-hydroxylase, and have been used as a biomarker for the detection of 21-hydroxylase deficiencies. |
Molecular Weight | 346.467 |
Formula | C21H30O4 |
CAS No. | 641-77-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Methanol: Slightly soluble
Chloroform: Slightly soluble
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21-Deoxycortisol 641-77-0 21 Deoxycortisol 21Deoxycortisol inhibitor inhibit