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Adamtsostatin 18

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Catalog No. T83171Cas No. 929554-95-0

Adamtsostatin 18, an anti-angiogenic peptide derived from proteins with type I thrombospondin motifs, suppresses cell migration and proliferation [1].

Adamtsostatin 18

Adamtsostatin 18

😃Good
Catalog No. T83171Cas No. 929554-95-0
Adamtsostatin 18, an anti-angiogenic peptide derived from proteins with type I thrombospondin motifs, suppresses cell migration and proliferation [1].
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Adamtsostatin 18, an anti-angiogenic peptide derived from proteins with type I thrombospondin motifs, suppresses cell migration and proliferation [1].
In vitro
Adamtsostatin 18, at concentrations of 0.01, 0.1, 1, 10, 20, 30, and 40 µg/mL administered over a period of three days, inhibits the proliferation of HUVEC cells [1].
Chemical Properties
Molecular Weight2145.38
FormulaC89H141N29O29S2
Cas No.929554-95-0
SmilesC([C@H](NC([C@@H](NC([C@H](CO)N)=O)CCCCN)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(NCC(NCC(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CCC(O)=O)=O)CCC(N)=O)=O)=O)CCCCN)=O)[C@@H](C)C)=O)=O)=O)=O)CS)=O)[C@@H](C)O)=O)CCCNC(=N)N)=O)CO)=O)CS)=O)CCC(O)=O)=O)CO)=O)C=2C=3C(NC2)=CC=CC3
Sequence ShortSKWSECSRTCGGGVKFQER
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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