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Cholic Acid

Name: Cholic Acid
Brand: TargetMol
SKU: T2963
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T2963Cas No. 81-25-4

Alias Colalin, Cholate, Cholanic acid

Cholic Acid (Cholate) is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. Cholic acid facilitates fat absorption and cholesterol excretion.

Cholic Acid

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Purity: 99.92%

Catalog No. T2963Alias Colalin, Cholate, Cholanic acidCas No. 81-25-4

Cholic Acid (Cholate) is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. Cholic acid facilitates fat absorption and cholesterol excretion.

Pack Size	Price	USA Warehouse	Global Warehouse
50 mg	$34	In Stock	In Stock
100 mg	$48	In Stock	In Stock
1 g	$68	In Stock	In Stock
5 g	$159	-	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:99.92%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Cholic Acid (Cholate) is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. Cholic acid facilitates fat absorption and cholesterol excretion.
Synonyms	Colalin, Cholate, Cholanic acid

Chemical Properties

Molecular Weight	408.57
Formula	C₂₄H₄₀O₅
Cas No.	81-25-4
Smiles	O[C@H]1[C@]2([C@]3([C@@](C)([C@@]([C@@H](CCC(O)=O)C)(CC3)[H])[C@@H](O)C[C@@]2([C@]4(C)[C@](C1)(C[C@H](O)CC4)[H])[H])[H])[H]
Relative Density.	1.128 g/cm3.
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (134.62 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.9 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4476 mL	12.2378 mL	24.4756 mL	122.3781 mL
5 mM	0.4895 mL	2.4476 mL	4.8951 mL	24.4756 mL
10 mM	0.2448 mL	1.2238 mL	2.4476 mL	12.2378 mL
20 mM	0.1224 mL	0.6119 mL	1.2238 mL	6.1189 mL
50 mM	0.0490 mL	0.2448 mL	0.4895 mL	2.4476 mL
100 mM	0.0245 mL	0.1224 mL	0.2448 mL	1.2238 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc