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Anti-IFNGR2 Antibody (8A302)
😃Good
Catalog No. TMAY-03393
Alias interferon γ receptor 2 (interferon γ transducer 1), interferon gamma receptor 2 (interferon gamma transducer 1), Ifgt, Ifgr2
Anti-IFNGR2 Antibody (8A302) is a Rabbit antibody targeting IFNGR2. Anti-IFNGR2 Antibody (8A302) can be used in ELISA.
Anti-IFNGR2 Antibody (8A302)
Anti-IFNGR2 Antibody (8A302)
😃Good
Catalog No. TMAY-03393Alias interferon γ receptor 2 (interferon γ transducer 1), interferon gamma receptor 2 (interferon gamma transducer 1), Ifgt, Ifgr2
Anti-IFNGR2 Antibody (8A302) is a Rabbit antibody targeting IFNGR2. Anti-IFNGR2 Antibody (8A302) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-IFNGR2 Antibody (8A302) is a Rabbit antibody targeting IFNGR2. Anti-IFNGR2 Antibody (8A302) can be used in ELISA. |
| Alias | interferon γ receptor 2 (interferon γ transducer 1), interferon gamma receptor 2 (interferon gamma transducer 1), Ifgt, Ifgr2 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 8A302 |
| Reactivity | Mouse |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IFNGR2 (rM IFNGR2; TMPY-02122; NP_032364.1; Met1-Val243). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Interferon-gamma receptor beta chain (IFNgammaR2), also known as IFNGR2, belongs to the type II cytokine receptor family, whose deficiency is a cause of autosomal recessive mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. This accessory factor is an integral part of the IFN-gamma signal transduction pathway and is likely to interact with GAF, JAK1, and/or JAK2. IFNGR2 is a component of the IFNgamma receptor complex along with the IFNgammaR alpha chain (IFNGR1) and is a new Bax suppressor. The C-terminal fragment (cytoplasmic domain) of IFNgammaR2 is expressed in human cancer cell lines of megakaryocytic cancer (DAMI), breast cancer (MDA-MD-468), and prostate cancer (PC3 cells). The Th1 cytokine IFNgamma, acting through its heterodimeric receptors, IFNgammaR1 and IFNgammaR2, in the induction/proliferation of Th1 cells, might suppress the Th2 responses that may underlie atopic asthma. IFNGR2 has always been seen as a key mechanism for shielding T lymphocytes from the antiproliferative effects of the IFNgamma-signal transducer and activator of the transcription 1 (STAT1) pathway. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Mouse IFNGR2 protein (TMPY-02122) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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