L-Triguluronic acid, a linear polysaccharide copolymer consisting of three L-guluronic acid (G) units, serves as a precursor for Alginate[1]. Alginate, an unbranched polyanionic polysaccharide, has applications in the development of delivery carriers for anti-fungal agents[2].

Alginate, a term for a group of polyanionic polysaccharides composed of β-d-mannuronic acid (M) and α-l-guluronic acid (G), features 1→4 linkages with homosequences of MMM and GGG, along with interdispersed MGM heterosequences[1]. Thanks to its non-toxic, biodegradable, biocompatible, mucoadhesive, and non-immunogenic qualities, alginate is extensively utilized in developing drug delivery systems. Furthermore, its application in alginate-based antifungal delivery systems holds significant promise for treating fungal infections in vivo[1].