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SLB1122168, an inhibitor targeting the sphingosine-1-phosphate (S1P) transporter Spns2 (with an IC50 of 94 nM for the mouse transporter), selectively reduces circulating lymphocyte counts without altering plasma S1P concentrations in mice at a dosage of 10 mg/kg.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $178 | 35 days | 35 days | |
| 5 mg | $772 | 35 days | 35 days | |
| 10 mg | $1,360 | 35 days | 35 days |
| Description | SLB1122168, an inhibitor targeting the sphingosine-1-phosphate (S1P) transporter Spns2 (with an IC50 of 94 nM for the mouse transporter), selectively reduces circulating lymphocyte counts without altering plasma S1P concentrations in mice at a dosage of 10 mg/kg. |
| Molecular Weight | 394.00 |
| Formula | C22H35N3O.HCl |
| Smiles | CCCCCCCCCCC1=CC=C2N=C(NC[C@@H]3CNCC3)OC2=C1.Cl |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Methanol: Soluble Ethanol: Soluble |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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