Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Glucocerebrosidase-IN-1 (compound 11a) is a potent and selective GCase (glucocerebrosidase) inhibitor, with an IC 50 of 29.3 μM and a K i of 18.5 μM. Due to GCase involvement in pathological disorders consequent to enzyme deficiency, Glucocerebrosidase-IN-1 can be used for the research of Gaucher disease (GD) and Parkinson’s disease (PD)[1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | Glucocerebrosidase-IN-1 (compound 11a) is a potent and selective GCase (glucocerebrosidase) inhibitor, with an IC 50 of 29.3 μM and a K i of 18.5 μM. Due to GCase involvement in pathological disorders consequent to enzyme deficiency, Glucocerebrosidase-IN-1 can be used for the research of Gaucher disease (GD) and Parkinson’s disease (PD)[1]. |
In vitro | Glucocerebrosidase-IN-1 (compound 11a) can enhance GCase activity 1.8-fold in fibroblasts bearing the homozygous L444P mutation [1]. |
Molecular Weight | 245.36 |
Formula | C13H27NO3 |
CAS No. | 2279945-76-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Glucocerebrosidase-IN-1 2279945-76-3 inhibitor inhibit