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Anti-IL-17F Antibody (1L340)
😃Good
Catalog No. TMAY-02106
Alias ML-1, ML1, interleukin 17F, IL-17F, CANDF6
Anti-IL-17F Antibody (1L340) is a Mouse antibody targeting IL-17F. Anti-IL-17F Antibody (1L340) can be used in ELISA.
Anti-IL-17F Antibody (1L340)
Anti-IL-17F Antibody (1L340)
😃Good
Catalog No. TMAY-02106Alias ML-1, ML1, interleukin 17F, IL-17F, CANDF6
Anti-IL-17F Antibody (1L340) is a Mouse antibody targeting IL-17F. Anti-IL-17F Antibody (1L340) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-IL-17F Antibody (1L340) is a Mouse antibody targeting IL-17F. Anti-IL-17F Antibody (1L340) can be used in ELISA. |
| Alias | ML-1, ML1, interleukin 17F, IL-17F, CANDF6 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 1L340 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL17F (rh IL17F; TMPY-01898; NP_443104.1; Arg31-Gln163). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Interleukin-17F (IL-17F) is a cytokine that shares sequence similarity with IL17. The most notable role of IL-17 is its involvement in inducing and mediating proinflammatory responses. IL-17 is commonly associated with allergic responses. IL-17F is expressed by activated T cells and was expressed only in activated CD4+ T cells and activated monocytes. IL-17F has been shown to stimulate the production of several other cytokines, including IL6 and IL8. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. Recombinant human IL-17F did not stimulate the proliferation of hematopoietic progenitors or the migration of mature leukocytes. However, it markedly inhibited the angiogenesis of human endothelial cells and induced endothelial cells to produce IL-2, TGF-{beta}, and monocyte chemoattractant protein-1. IL-17F stimulates the production of other cytokines and granulocyte colony-stimulating factor and can regulate cartilage matrix turnover. IL-17F stimulates PBMC and T-cell proliferation. It also functions in inhibiting angiogenesis By similarity. IL-17F plays a role in the induction of neutrophilia in the lungs and the exacerbation of antigen-induced pulmonary allergic inflammation. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human IL17F Protein (TMPY-01898) |
| Antigen Species | Human |
| Biology Area | Neuroinflammation |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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