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Anti-TXN Antibody (7Z328)
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Catalog No. TMAY-03478
Alias TXN, TRX1, TRX, TRDX, Thioredoxin, Surface-Associated Sulphydryl Protein, SASP, ATL-Derived Factor, ADF
Anti-TXN Antibody (7Z328) is a Rabbit antibody targeting TXN. Anti-TXN Antibody (7Z328) can be used in WB,ELISA.
Anti-TXN Antibody (7Z328)
Anti-TXN Antibody (7Z328)
😃Good
Catalog No. TMAY-03478Alias TXN, TRX1, TRX, TRDX, Thioredoxin, Surface-Associated Sulphydryl Protein, SASP, ATL-Derived Factor, ADF
Anti-TXN Antibody (7Z328) is a Rabbit antibody targeting TXN. Anti-TXN Antibody (7Z328) can be used in WB,ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-TXN Antibody (7Z328) is a Rabbit antibody targeting TXN. Anti-TXN Antibody (7Z328) can be used in WB,ELISA. |
| Alias | TXN, TRX1, TRX, TRDX, Thioredoxin, Surface-Associated Sulphydryl Protein, SASP, ATL-Derived Factor, ADF |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 7Z328 |
| Reactivity | Mouse |
| Verified Activity | Anti-Txn rabbit monoclonal antibody at 1:500 dilution. -Lane A: Hela Whole Cell Lysate. -Lane B: A431 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. -Predicted band size:27 kDa. -Observed band size:27 kDa |
| Application | WB,ELISA |
| Recommended Dose | WB: 1:500-1:1000; ELISA: 1:25000-1:50000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Thioredoxin/TXN/SASP (rM Thioredoxin/TXN/SASP; TMPY-00382; P10639; Met1-Val105). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Thioredoxin, also known as ATL-derived factor, Surface-associated sulphydryl protein, SASP and TXN, is a nucleus, cytoplasm and secreted protein that belongs to the thioredoxin family. Thioredoxins are proteins that act as antioxidants by facilitating the reduction of other proteins by cysteine thiol-disulfide exchange. Thioredoxins are found in nearly all known organisms and are essential for life in mammals. Thioredoxin / TXN participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Thioredoxin / TXN plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Thioredoxin / TXN nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Thioredoxin / TXN induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Mouse Thioredoxin/TXN/SASP Protein (TMPY-00382) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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