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Anti-FSTL1 Antibody-FITC (7R231) is a FITC-conjugated Rabbit antibody targeting FSTL1. Anti-FSTL1 Antibody-FITC (7R231) can be used in FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 T | $104 | 7-10 days | |
100 T | $210 | 7-10 days |
Description | Anti-FSTL1 Antibody-FITC (7R231) is a FITC-conjugated Rabbit antibody targeting FSTL1. Anti-FSTL1 Antibody-FITC (7R231) can be used in FCM. |
Alias | TSC-36, Fstl, follistatin-like 1, AW107808, AI316791 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 7R231 |
Reactivity | Human |
Verified Activity | Flow cytometric analysis of Human FSTL1 expression on HeLa cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with FITC-conjugated anti-Human FSTL1. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
Application | FCM |
Recommended Dose | 10 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human FSTL1 (rh FSTL1; TMPY-01106; NP_009016.1; Met1-Ile308) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
Research Background | Follistatin-related protein 1 (FSTL1) is an extracellular glycoprotein whose functional significance in physiological and pathological processes is incompletely understood. Recently, we have shown that FSTL1 acts as a muscle-derived secreted factor that is up-regulated by Akt activation and ischemic stress and that FSTL1 exerts favorable actions on the heart and vasculature. Here, we sought to identify the receptor that mediates the cellular actions of FSTL1. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. FSTL1 is thought to be an autoantigen associated with rheumatoid arthritis. DIP2A functions as a novel receptor that mediates the cardiovascular protective effects of FSTL1. Experiment results have provided in vivo and in vitro evidence to demonstrate that Fstl1 modulates lung development and alveolar maturation, in part, through BMP4 signaling. |
Conjucates | FITC |
Others Formats | Unconjugated |
Antibody Types Available | 2 |
Immunogen | Recombinant Human FSTL1 Protein (TMPY-01106) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
Transport | Shipping with blue ice. |
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