keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nona-L-arginine (Arg)9 acetate, a cell-penetrating peptide (CPP) consisting of 9 arginine residues, displays neuroprotective properties, with an IC50 of 0.78 μM in the glutamic acid model [1] [2].
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Description | Nona-L-arginine (Arg)9 acetate, a cell-penetrating peptide (CPP) consisting of 9 arginine residues, displays neuroprotective properties, with an IC50 of 0.78 μM in the glutamic acid model [1] [2]. |
In vitro | (Arg)9 acetate, at concentrations of 5-10 μM, demonstrates substantial dose-dependent neuroprotection against glutamic acid exposure, with an IC50 value of 0.78 μM. Its neuroprotective efficacy is reduced in the kainic acid model, exhibiting an IC50 of 0.81 μM. Moreover, it provides neuroprotection in in vitro ischemic conditions, with an IC50 of 6 μM [1]. |
In vivo | The compound '(Arg)9' (Nona-L-arginine; administered intravenously at 1 μM/kg in a volume of 600 μL; once for 30 minutes) exhibits neuroprotective properties and decreases infarct size in male Sprague-Dawley rats using a permanent middle cerebral artery stroke model [2]. |
Synonyms | Peptide R9 acetate, Nona-L-arginine acetate |
Molecular Weight | 1483.74 |
Formula | C56H114N36O12 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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(Arg)9 acetate (Arg)9 Acetate Peptide R9 acetate Nona-L-arginine acetate Nona-L-arginine Acetate Peptide R9 Acetate inhibitor inhibit