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Nona-L-arginine (Arg)9 acetate, a cell-penetrating peptide (CPP) consisting of 9 arginine residues, displays neuroprotective properties, with an IC50 of 0.78 μM in the glutamic acid model [1] [2].
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| Description | Nona-L-arginine (Arg)9 acetate, a cell-penetrating peptide (CPP) consisting of 9 arginine residues, displays neuroprotective properties, with an IC50 of 0.78 μM in the glutamic acid model [1] [2]. | 
| In vitro | (Arg)9 acetate, at concentrations of 5-10 μM, demonstrates substantial dose-dependent neuroprotection against glutamic acid exposure, with an IC50 value of 0.78 μM. Its neuroprotective efficacy is reduced in the kainic acid model, exhibiting an IC50 of 0.81 μM. Moreover, it provides neuroprotection in in vitro ischemic conditions, with an IC50 of 6 μM [1]. | 
| In vivo | The compound '(Arg)9' (Nona-L-arginine; administered intravenously at 1 μM/kg in a volume of 600 μL; once for 30 minutes) exhibits neuroprotective properties and decreases infarct size in male Sprague-Dawley rats using a permanent middle cerebral artery stroke model [2]. | 
| Synonyms | Peptide R9 acetate, Nona-L-arginine acetate | 
| Molecular Weight | 1483.74 | 
| Formula | C56H114N36O12 | 
| Sequence Short | RRRRRRRRR | 
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | 
 For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL .
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL .  A total of 10 animals were administered, and the formula you used is 5%
 A total of 10 animals were administered, and the formula you used is 5%  DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。 (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
 (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first. main solution, add 300 μLPEG300
 main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O
 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
 mix well and clarify
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