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Anti-CX3CL1/Fractalkine Antibody (7B389)
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Catalog No. TMAY-01041
Alias chemokine (C-X3-C motif) ligand 1
Anti-CX3CL1/Fractalkine Antibody (7B389) is a Mouse antibody targeting CX3CL1/Fractalkine. Anti-CX3CL1/Fractalkine Antibody (7B389) can be used in ELISA.
Anti-CX3CL1/Fractalkine Antibody (7B389)
Anti-CX3CL1/Fractalkine Antibody (7B389)
😃Good
Catalog No. TMAY-01041Alias chemokine (C-X3-C motif) ligand 1
Anti-CX3CL1/Fractalkine Antibody (7B389) is a Mouse antibody targeting CX3CL1/Fractalkine. Anti-CX3CL1/Fractalkine Antibody (7B389) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA Reactivity: Human |
| Alias | chemokine (C-X3-C motif) ligand 1 |
| Ig Type | Mouse IgG1 |
| Clone | 7B389 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CX3CL1 extracellular domain (rhCX3CL1; TMPY-00737; NP_002987.1; Met 1-Arg 339). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Fractalkine or Chemokine (C-X3-C motif) ligand 1 (CX3CL1) is a member of the CX3C chemokine family. Fractalkine / CX3CL1 is a unique chemokine that functions not only as a chemoattractant but also as an adhesion molecule and is expressed on endothelial cells activated by proinflammatory cytokines, such as interferon-gamma and tumor necrosis factor-alpha. Fractalkine/CX3CL1 is expressed in a membrane-bound form on activated endothelial cells and mediates attachment and firm adhesion of T cells, monocytes and NK cells. Fractalkine / CX3CL1 is associated with dendritic cells (DC) in epidermis and lymphoid organs. The fractalkine receptor, CX3CR1, is expressed on cytotoxic effector lymphocytes, including natural killer (NK) cells and cytotoxic T lymphocytes, which contain high levels of intracellular perforin and granzyme B, and on macrophages. Soluble fractalkine causes migration of NK cells, cytotoxic T lymphocytes, and macrophages, whereas the membrane-bound form captures and enhances the subsequent migration of these cells in response to secondary stimulation with other chemokines. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human CX3CL1 protein (TMPY-00737) |
| Antigen Species | Human |
| Biology Area | Neuroinflammation |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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