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Figitumumab
🥰Excellent
Catalog No. T76746Cas No. 943453-46-1
Alias CP-751871
Figitumumab (CP-751871) is a highly potent, fully human monoclonal antibody of the IgG2 isotype that specifically targets the insulin-like growth factor 1 receptor (IGF1R). it functions by competitively inhibiting the binding of IGF1 to its receptor with a IC50 of 1.8 nM. Figitumumab can be used in studies about advanced squamous cell carcinoma of the lung.
Figitumumab
Figitumumab
🥰Excellent
Purity: 95%
Catalog No. T76746Alias CP-751871Cas No. 943453-46-1
Figitumumab (CP-751871) is a highly potent, fully human monoclonal antibody of the IgG2 isotype that specifically targets the insulin-like growth factor 1 receptor (IGF1R). it functions by competitively inhibiting the binding of IGF1 to its receptor with a IC50 of 1.8 nM. Figitumumab can be used in studies about advanced squamous cell carcinoma of the lung.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $247 | In Stock | |
| 5 mg | $747 | In Stock | |
| 10 mg | $1,200 | In Stock |
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Concentration:9.659 mg/mL
Purity:95%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Figitumumab (CP-751871) is a highly potent, fully human monoclonal antibody of the IgG2 isotype that specifically targets the insulin-like growth factor 1 receptor (IGF1R). it functions by competitively inhibiting the binding of IGF1 to its receptor with a IC50 of 1.8 nM. Figitumumab can be used in studies about advanced squamous cell carcinoma of the lung. |
| In vitro | Figitumumab (CP-751871) (152 pM-10 μM, 3 days) can inhibit cancer cell proliferation. [1] |
| Synonyms | CP-751871 |
| Cas No. | 943453-46-1 |
| Color | Transparent |
| Appearance | Liquid |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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