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Zymostenol

Name: Zymostenol
Brand: TargetMol
SKU: T35321
Rating: 4.5 (1 reviews)

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Catalog No. T35321Cas No. 566-97-2

Alias Δ8-Cholesterol, delta(8)-Cholestenol, 5a-Cholest-8-en-3b-ol

Zymostenol (5a-Cholest-8-en-3b-ol) is a RORγ agonist with an EC50 of 1 μM and serves as a late-stage precursor in cholesterol biosynthesis.

Zymostenol

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Catalog No. T35321Alias Δ8-Cholesterol, delta(8)-Cholestenol, 5a-Cholest-8-en-3b-olCas No. 566-97-2

Zymostenol (5a-Cholest-8-en-3b-ol) is a RORγ agonist with an EC50 of 1 μM and serves as a late-stage precursor in cholesterol biosynthesis.

Pack Size	Price	Availability
5 mg	$263	35 days
10 mg	$468	35 days
25 mg	$987	35 days
50 mg	$1,930	35 days

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Product Introduction

Bioactivity

Description	Zymostenol (5a-Cholest-8-en-3b-ol) is a RORγ agonist with an EC50 of 1 μM and serves as a late-stage precursor in cholesterol biosynthesis.
Targets&IC50	RORγ:1 μM(EC50)
In vitro	Zymostenol (12-104 μM) promotes the formation of myelin basic protein-positive (MBP+) oligodendrocytes in mouse ectodermal stem cell-derived oligodendrocyte progenitors.[2] Zymostenol (20 μM, 3 days) arrests the MCF-7 cell cycle in the G0-G1 phase.[3]
Synonyms	Δ8-Cholesterol, delta(8)-Cholestenol, 5a-Cholest-8-en-3b-ol

Chemical Properties

Molecular Weight	386.65
Formula	C₂₇H₄₆O
Cas No.	566-97-2
Smiles	C[C@@]12[C@](C3=C([C@]4(C)[C@@](CC3)(C[C@@H](O)CC4)[H])CC1)(CC[C@@]2([C@@H](CCCC(C)C)C)[H])[H]
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

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mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

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