Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GNF2133 hydrochloride is a selective, effective, and orally active DYRK1A inhibitor, able to act on DYRK1A (IC50: 0.0062 μM) and GSK3β (IC50< 50 μM); GNF2133 hydrochloride showed good proliferative ability and efficacy in rat and human primary β cells. GNF2133 hydrochloride significantly improved glucose processing ability and increased insulin secretion. GNF2133 hydrochloride has the potential to study type 1 diabetes.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,530.00 | |
50 mg | 6-8 weeks | $ 1,990.00 | |
100 mg | 6-8 weeks | $ 3,230.00 |
Description | GNF2133 hydrochloride is a selective, effective, and orally active DYRK1A inhibitor, able to act on DYRK1A (IC50: 0.0062 μM) and GSK3β (IC50> 50 μM); GNF2133 hydrochloride showed good proliferative ability and efficacy in rat and human primary β cells. GNF2133 hydrochloride significantly improved glucose processing ability and increased insulin secretion. GNF2133 hydrochloride has the potential to study type 1 diabetes. |
Molecular Weight | 471.0 |
Formula | C24H31ClN6O2 |
CAS No. | 2561414-57-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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GNF2133 hydrochloride 2561414-57-9 inhibitor inhibit