Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JBI-589 is an isoform-selective, non-covalent inhibitor of PAD4 that diminishes CXCR2 expression and impedes neutrophil chemotaxis. Additionally, it attenuates primary tumor growth and metastases, augmenting the efficacy of checkpoint inhibitors [1].
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Description | JBI-589 is an isoform-selective, non-covalent inhibitor of PAD4 that diminishes CXCR2 expression and impedes neutrophil chemotaxis. Additionally, it attenuates primary tumor growth and metastases, augmenting the efficacy of checkpoint inhibitors [1]. |
Molecular Weight | 481.56 |
Formula | C29H28FN5O |
CAS No. | 2308504-22-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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JBI-589 2308504-22-3 inhibitor inhibit