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Diclone

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Catalog No. T7074Cas No. 117-80-6

2, 3-Dichloro-1, 4-naphthoquinone is an inhibitor of Itch, a HECT domain-E3 ligase. It is also used in pesticide formulations.

Diclone

Diclone

🥰Excellent
Purity: 99.02%
Catalog No. T7074Cas No. 117-80-6
2, 3-Dichloro-1, 4-naphthoquinone is an inhibitor of Itch, a HECT domain-E3 ligase. It is also used in pesticide formulations.
Pack SizePriceAvailabilityQuantity
5 mg$41 In Stock
10 mg$58 In Stock
25 mg$93 In Stock
50 mg$136 In Stock
100 mg$196 In Stock
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Purity:99.02%
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COA HNMR HPLC
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Product Introduction

Bioactivity
Description
2, 3-Dichloro-1, 4-naphthoquinone is an inhibitor of Itch, a HECT domain-E3 ligase. It is also used in pesticide formulations.
Chemical Properties
Molecular Weight227.04
FormulaC10H4Cl2O2
Cas No.117-80-6
SmilesClC1=C(Cl)C(=O)C2=C(C=CC=C2)C1=O
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 22.5 mg/mL (99.1 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.4045 mL22.0226 mL44.0451 mL220.2255 mL
5 mM0.8809 mL4.4045 mL8.8090 mL44.0451 mL
10 mM0.4405 mL2.2023 mL4.4045 mL22.0226 mL
20 mM0.2202 mL1.1011 mL2.2023 mL11.0113 mL
50 mM0.0881 mL0.4405 mL0.8809 mL4.4045 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

ubiquitin E3 ligase HECTD2Diclone
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