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(E/Z)-GSK-3β inhibitor 1

Name: (E/Z)-GSK-3β inhibitor 1
Brand: TargetMol
SKU: T9178
Price: 32 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T9178Cas No. 3367-88-2

Alias GSK-3β inhibitor 1

(E/Z)-GSK-3β inhibitor 1 is a glycogen synthase kinase 3β (GSK-3β) inhibitor demonstrating high antidiabetic efficacy.

(E/Z)-GSK-3β inhibitor 1

🥰Excellent

Purity: 98.60%

Catalog No. T9178Alias GSK-3β inhibitor 1Cas No. 3367-88-2

(E/Z)-GSK-3β inhibitor 1 is a glycogen synthase kinase 3β (GSK-3β) inhibitor demonstrating high antidiabetic efficacy.

Pack Size	Price	Availability
2 mg	$32	In Stock
5 mg	$54	In Stock
10 mg	$90	In Stock
25 mg	$165	In Stock
50 mg	$247	In Stock
100 mg	$353	In Stock
200 mg	$480	In Stock
1 mL x 10 mM (in DMSO)	$60	In Stock

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Batch Information

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Purity:98.60%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	(E/Z)-GSK-3β inhibitor 1 is a glycogen synthase kinase 3β (GSK-3β) inhibitor demonstrating high antidiabetic efficacy.
Targets&IC50	GSK-3β:4.9 nM
Synonyms	GSK-3β inhibitor 1

Chemical Properties

Molecular Weight	222.24
Formula	C₁₄H₁₀N₂O
Cas No.	3367-88-2
Smiles	O=C1Nc2ccccc2\C1=C\c1ccccn1
Relative Density.	1.291g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 49 mg/mL (220.48 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.4996 mL	22.4982 mL	44.9964 mL	224.9820 mL
5 mM	0.8999 mL	4.4996 mL	8.9993 mL	44.9964 mL
10 mM	0.4500 mL	2.2498 mL	4.4996 mL	22.4982 mL
20 mM	0.2250 mL	1.1249 mL	2.2498 mL	11.2491 mL
50 mM	0.0900 mL	0.4500 mL	0.8999 mL	4.4996 mL
100 mM	0.0450 mL	0.2250 mL	0.4500 mL	2.2498 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc