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Eriocitrin

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Catalog No. T6S0221Cas No. 13463-28-0
Alias Eriodictyol-7-O-Rutinoside, Eriodictyol glycoside, eriodictyol 7-rutinoside, Eriodictioside

1. Eriocitrin (Eriodictyol-7-O-Rutinoside) is powerful antioxidative flavonoid; (1) Prevents oxidative damages caused by acute exercise-induced oxidative stress.(2) Lipid-lowering effects in a rat model of high-fat diet. 2. Dietary Eriocitrin ameliorates diet-induced hepatic steatosis with activation of mitochondrial biogenesis. 3. Eriocitrin and Apigenin were identified as new potent inhibitors of human carbonic anhydrase VA isozyme.

Eriocitrin

Eriocitrin

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Purity: 99.96%
Catalog No. T6S0221Alias Eriodictyol-7-O-Rutinoside, Eriodictyol glycoside, eriodictyol 7-rutinoside, EriodictiosideCas No. 13463-28-0
1. Eriocitrin (Eriodictyol-7-O-Rutinoside) is powerful antioxidative flavonoid; (1) Prevents oxidative damages caused by acute exercise-induced oxidative stress.(2) Lipid-lowering effects in a rat model of high-fat diet. 2. Dietary Eriocitrin ameliorates diet-induced hepatic steatosis with activation of mitochondrial biogenesis. 3. Eriocitrin and Apigenin were identified as new potent inhibitors of human carbonic anhydrase VA isozyme.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$31In StockIn Stock
5 mg$69In StockIn Stock
10 mg$125In StockIn Stock
25 mg$198In StockIn Stock
50 mg$328In StockIn Stock
100 mg$496In StockIn Stock
200 mg$693-In Stock
1 mL x 10 mM (in DMSO)$93In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.96%
Appearance:Solid
Color:White to Yellow
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Product Introduction

Eriocitrin AI Summary
Eriocitrin exhibits multiple bioactivities and toxicological properties. It inhibits electric eel acetylcholinesterase (AChE) at 2 mg/ml with a 21.54% inhibition rate and horse butyrylcholinesterase (BChE) with a 1.98% inhibition rate at the same concentration. The compound shows notable cytotoxicity, achieving 75.2% activity against human HL cells at 50 µM after 72 hours of exposure. Additionally, it possesses antichlamydial activity against Chlamydia pneumoniae K7 in HL cells, inhibiting the pathogen by 8.6% at 50 µM after 70 hours. Eriocitrin also inhibits dipeptidyl peptidase-4 (DPP4) activity with an IC50 value of 10360.0 nM, as determined through a luminescence assay using Gly-Pro-AMC substrate after 4 seconds of preincubation. Furthermore, it shows toxicity in denervated C57BL/6NCrSlc mice, which is indicated by a body weight change of 25.37 g..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
1. Eriocitrin (Eriodictyol-7-O-Rutinoside) is powerful antioxidative flavonoid; (1) Prevents oxidative damages caused by acute exercise-induced oxidative stress.(2) Lipid-lowering effects in a rat model of high-fat diet. 2. Dietary Eriocitrin ameliorates diet-induced hepatic steatosis with activation of mitochondrial biogenesis. 3. Eriocitrin and Apigenin were identified as new potent inhibitors of human carbonic anhydrase VA isozyme.
SynonymsEriodictyol-7-O-Rutinoside, Eriodictyol glycoside, eriodictyol 7-rutinoside, Eriodictioside
Chemical Properties
Molecular Weight596.53
FormulaC27H32O15
Cas No.13463-28-0
SmilesC[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3cc(O)c4C(=O)C[C@H](Oc4c3)c3ccc(O)c(O)c3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O
Relative Density.1.77 g/cm3
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Pyridine, Methanol, etc.: Soluble
DMSO: 91 mg/mL (152.55 mM), Sonication is recommended.
Ethanol: Soluble
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (5.53 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.6764 mL8.3818 mL16.7636 mL83.8181 mL
5 mM0.3353 mL1.6764 mL3.3527 mL16.7636 mL
10 mM0.1676 mL0.8382 mL1.6764 mL8.3818 mL
20 mM0.0838 mL0.4191 mL0.8382 mL4.1909 mL
50 mM0.0335 mL0.1676 mL0.3353 mL1.6764 mL
100 mM0.0168 mL0.0838 mL0.1676 mL0.8382 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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