Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-IGF2R Domain 1-3 Antibody (3T816)

😃Good
Catalog No. TMAC-02441

Anti-IGF2R Domain 1-3 Antibody (3T816) is a Rabbit antibody targeting IGF2R Domain 1-3. Anti-IGF2R Domain 1-3 Antibody (3T816) can be used in WB,ICC/IF,IHC,IP,FCM.

Anti-IGF2R Domain 1-3 Antibody (3T816)

Anti-IGF2R Domain 1-3 Antibody (3T816)

😃Good
Catalog No. TMAC-02441
Anti-IGF2R Domain 1-3 Antibody (3T816) is a Rabbit antibody targeting IGF2R Domain 1-3. Anti-IGF2R Domain 1-3 Antibody (3T816) can be used in WB,ICC/IF,IHC,IP,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4987-10 days
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View More

Product Introduction

Bioactivity
Description
Anti-IGF2R Domain 1-3 Antibody (3T816) is a Rabbit antibody targeting IGF2R Domain 1-3. Anti-IGF2R Domain 1-3 Antibody (3T816) can be used in WB,ICC/IF,IHC,IP,FCM.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000-10000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe mannose 6-phosphate/insulin-like growth factor II receptor, IGF-IIR (also designated M6P/IGF2R), is a ubiquitously expressed integral glycoprotein. By binding glycoproteins through two of its extracytoplasmic domains, IGF-IIR mediates the activation of TGF??1 (a growth inhibitor), the degradation of IGF-II and the transport of lysosomal enzymes. Subsequently, IGF-IIR can form oligomeric complexes, which increase the affinity of IGF-IIR for lysosomal enzymes. Unlike IGF-IR, IGF-IIR does not potentiate the signaling of IGF-I or IGF-II, which have mitogenic, cell survival and insulin-like effects. Therefore, IGF-IIR is characterized as a tumor suppressor. Furthermore, the IGF-IIR gene is located on chromosome 6q26, which is commonly mutated or deleted in several human cancers.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 274 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-IGF2R Domain 1-3 Antibody (3T816) | purchase Anti-IGF2R Domain 1-3 Antibody (3T816) | Anti-IGF2R Domain 1-3 Antibody (3T816) cost | order Anti-IGF2R Domain 1-3 Antibody (3T816) | Anti-IGF2R Domain 1-3 Antibody (3T816) molecular weight