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Anti-REG1B Antibody (6Q539) is a Rabbit antibody targeting REG1B. Anti-REG1B Antibody (6Q539) can be used in ELISA(Cap).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
20 μL | $94 | 7-10 days | |
100 μL | $269 | 7-10 days |
Description | Anti-REG1B Antibody (6Q539) is a Rabbit antibody targeting REG1B. Anti-REG1B Antibody (6Q539) can be used in ELISA(Cap). |
Alias | regenerating islet-derived 1 β, regenerating islet-derived 1 beta |
Ig Type | Monoclonal Rabbit IgG |
Clone | 6Q539 |
Reactivity | Human |
Application | ELISA(Cap) |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human REG1B (rh REG1B; TMPY-01394; NP_006498.1; Met1-Asn166). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Regenerating gene (Reg), first isolated from a regenerating islet cDNA library, encodes a secretory protein with a growth stimulating effect on pancreatic beta cells, and could be associated with fibrocalculous pancreatopathy. Reg and Reg-related genes which were expressed in various organs have been revealed to constitute a multigene family, the Reg family consisting of four subtypes (types I, II, III, IV) and are involved in cancers and neurodegenerative diseases. Regenerating islet-derived 1 beta (REG1B), also known as Lithostathine-1-beta and Pancreatic stone protein 2 (PSPS2), is a types I Reg protein and contains one typical C-type lectin domain. REG1B is a 166-amino acid protein that has 22 amino acid substitutions in comparison with the previously isolated human REG1A, and it is was expressed only in pancreas. REG1B Is normally found in the exocrine pancreas, whereas in other tissues it appears either only under pathological conditions, such as Alzheimer's disease (brain), cancer (colon), or during regeneration such as neuronal sprouting in brain and pancreas regeneration. REG1B might act as an inhibitor of spontaneous calcium carbonate precipitation. The REG1A and REG1B gene and proteins could play different roles in the pancreas. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human REG1B Protein (TMPY-01394) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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