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Acanthoside B

Name: Acanthoside B
Brand: TargetMol
SKU: TN1355
Price: 68 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN1355Cas No. 7374-79-0

Acanthoside B is a lignan with anti-inflammatory and anti-amnesic effects. Acanthoside B can be used for studies about Alzheimer's disease and lung inflammation.

Acanthoside B

🥰Excellent

Purity: 99.84%

Catalog No. TN1355Cas No. 7374-79-0

Acanthoside B is a lignan with anti-inflammatory and anti-amnesic effects. Acanthoside B can be used for studies about Alzheimer's disease and lung inflammation.

Pack Size	Price	Availability
1 mg	$68	In Stock
5 mg	$163	In Stock
10 mg	$247	In Stock
25 mg	$396	In Stock
50 mg	$589	In Stock
1 mL x 10 mM (in DMSO)	$132	In Stock

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Purity:99.84%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Acanthoside B is a lignan with anti-inflammatory and anti-amnesic effects. Acanthoside B can be used for studies about Alzheimer's disease and lung inflammation.
In vitro	Acanthoside B has inhibitory effects on the allergic inflammation[1].
In vivo	Acanthoside B restores the cholinergic activity, decreases the endogenous antioxidant status, suppresses neuroinflammation, and activates the TrkB/CREB/BDNF pathway thereby attenuating Scopolamine inflicted AD-like amnesic traits in mice[2].

Chemical Properties

Molecular Weight	580.58
Formula	C₂₈H₃₆O₁₃
Cas No.	7374-79-0
Smiles	[H][C@]12CO[C@]([H])(c3cc(OC)c(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(OC)c3)[C@@]1([H])CO[C@]2([H])c1cc(OC)c(O)c(OC)c1
Relative Density.	1.399 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (86.12 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (3.44 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7224 mL	8.6121 mL	17.2242 mL	86.1208 mL
5 mM	0.3445 mL	1.7224 mL	3.4448 mL	17.2242 mL
10 mM	0.1722 mL	0.8612 mL	1.7224 mL	8.6121 mL
20 mM	0.0861 mL	0.4306 mL	0.8612 mL	4.3060 mL
50 mM	0.0344 mL	0.1722 mL	0.3445 mL	1.7224 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc