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MLS0315771 is an effective and biologically active competitive phosphomannose isomerase (MPI) inhibitor (IC50: ~1 μM and a Ki: 1.4 μM).

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $48 | In Stock | In Stock | |
| 5 mg | $113 | In Stock | In Stock | |
| 10 mg | $172 | In Stock | In Stock | |
| 25 mg | $322 | In Stock | In Stock | |
| 50 mg | $428 | In Stock | In Stock | |
| 100 mg | $572 | In Stock | In Stock | |
| 1 mL x 10 mM (in DMSO) | $125 | In Stock | In Stock |
| Description | MLS0315771 is an effective and biologically active competitive phosphomannose isomerase (MPI) inhibitor (IC50: ~1 μM and a Ki: 1.4 μM). |
| Targets&IC50 | MPI:1 μM (IC50) |
| In vitro | MLS0315771 is toxic to the zebrafish embryos above 2 μM. MLS0315771 toxicity at higher concentrations is an off-target effect. MLS0315771 enhances mannose flux toward glycosylation. It ~50% of embryos appeared sick within 20 min at 8-10 μM, and most of them die by 30-60 min. |
| Molecular Weight | 273.33 |
| Formula | C15H12FNOS |
| Cas No. | 727664-91-7 |
| Smiles | Cc1ccc(C)c(c1)-n1sc2cc(F)ccc2c1=O |
| Relative Density. | no data available |
| Color | White |
| Appearance | Solid |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 11 mg/mL (40.24 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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