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FLT3 kinase inhibitor 2HCl

Name: FLT3 kinase inhibitor 2HCl
Brand: TargetMol
SKU: T50072
Price: 57 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T50072Cas No. 2411178-94-2

3-amino-1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one dihydrochloride is used in the synthesis of various compounds.

FLT3 kinase inhibitor 2HCl

🥰Excellent

Purity: 97.12%

Catalog No. T50072Cas No. 2411178-94-2

3-amino-1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one dihydrochloride is used in the synthesis of various compounds.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$57	In Stock	In Stock
5 mg	$131	In Stock	In Stock
10 mg	$197	In Stock	In Stock
25 mg	$337	In Stock	In Stock
50 mg	$473	In Stock	In Stock
100 mg	$672	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$167	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:97.12%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

3-amino-1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one dihydrochloride is used in the synthesis of various compounds.

Chemical Properties

Molecular Weight	530.449
Formula	C₂₅H₂₉Cl₂N₇O₂
Cas No.	2411178-94-2
Smiles	Cl.Cl.NCCC(=O)N1CCC[C@H](C1)n1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (94.26 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8852 mL	9.4260 mL	18.8520 mL	94.2598 mL
5 mM	0.3770 mL	1.8852 mL	3.7704 mL	18.8520 mL
10 mM	0.1885 mL	0.9426 mL	1.8852 mL	9.4260 mL
20 mM	0.0943 mL	0.4713 mL	0.9426 mL	4.7130 mL
50 mM	0.0377 mL	0.1885 mL	0.3770 mL	1.8852 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

3amino1[(3R)3[4amino3(4phenoxyphenyl)1Hpyrazolo[3,4d]pyrimidin1yl]piperidin1yl]propan1one dihydrochloride3 amino 1 [(3R) 3 [4 amino 3 (4 phenoxyphenyl) 1H pyrazolo[3,4 d]pyrimidin 1 yl]piperidin 1 yl]propan 1 one dihydrochloride