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FLT3 kinase inhibitor 2HCl

🥰Excellent
Catalog No. T50072Cas No. 2411178-94-2

3-amino-1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one dihydrochloride is used in the synthesis of various compounds.

FLT3 kinase inhibitor 2HCl

FLT3 kinase inhibitor 2HCl

🥰Excellent
Purity: 97.12%
Catalog No. T50072Cas No. 2411178-94-2
3-amino-1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one dihydrochloride is used in the synthesis of various compounds.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$57In StockIn Stock
5 mg$131In StockIn Stock
10 mg$197In StockIn Stock
25 mg$337In StockIn Stock
50 mg$473In StockIn Stock
100 mg$672In StockIn Stock
1 mL x 10 mM (in DMSO)$167In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:97.12%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
3-amino-1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one dihydrochloride is used in the synthesis of various compounds.
Chemical Properties
Molecular Weight530.449
FormulaC25H29Cl2N7O2
Cas No.2411178-94-2
SmilesCl.Cl.NCCC(=O)N1CCC[C@H](C1)n1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12
Relative Density.no data available
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (94.26 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.8852 mL9.4260 mL18.8520 mL94.2598 mL
5 mM0.3770 mL1.8852 mL3.7704 mL18.8520 mL
10 mM0.1885 mL0.9426 mL1.8852 mL9.4260 mL
20 mM0.0943 mL0.4713 mL0.9426 mL4.7130 mL
50 mM0.0377 mL0.1885 mL0.3770 mL1.8852 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

3amino1[(3R)3[4amino3(4phenoxyphenyl)1Hpyrazolo[3,4d]pyrimidin1yl]piperidin1yl]propan1one dihydrochloride3 amino 1 [(3R) 3 [4 amino 3 (4 phenoxyphenyl) 1H pyrazolo[3,4 d]pyrimidin 1 yl]piperidin 1 yl]propan 1 one dihydrochloride
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