Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BAY-747 (BAY 1165747) is an orally administered, brain-penetrant compound that stimulates soluble guanylate cyclase (sGC). It effectively counteracts memory impairments induced by L-NAME and improves cognitive performance in rats during the object location task (OLT). Additionally, BAY-747 reduces blood pressure in conscious normotensive and spontaneously hypertensive rats (SHR) and enhances skeletal muscle function in the mdx/mTRG2 mouse model of Duchenne muscular dystrophy (DMD) [1] [2] [3].
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Description | BAY-747 (BAY 1165747) is an orally administered, brain-penetrant compound that stimulates soluble guanylate cyclase (sGC). It effectively counteracts memory impairments induced by L-NAME and improves cognitive performance in rats during the object location task (OLT). Additionally, BAY-747 reduces blood pressure in conscious normotensive and spontaneously hypertensive rats (SHR) and enhances skeletal muscle function in the mdx/mTRG2 mouse model of Duchenne muscular dystrophy (DMD) [1] [2] [3]. |
Molecular Weight | 416.46 |
Formula | C22H26F2N4O2 |
CAS No. | 1609342-18-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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BAY-747 1609342-18-8 inhibitor inhibit