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Trovirdine

Name: Trovirdine
Brand: TargetMol
SKU: T3172
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T3172Cas No. 149488-17-5

Alias LY300046

Trovirdine (LY300046) is a thiourea non-nucleoside reverse transcriptase inhibitor.

Trovirdine

🥰Excellent

Purity: 98.50%

Catalog No. T3172Alias LY300046Cas No. 149488-17-5

Trovirdine (LY300046) is a thiourea non-nucleoside reverse transcriptase inhibitor.

Pack Size	Price	Availability
2 mg	$34	In Stock
5 mg	$55	In Stock
10 mg	$97	In Stock
25 mg	$197	In Stock
50 mg	$328	In Stock
100 mg	$496	In Stock
1 mL x 10 mM (in DMSO)	$61	In Stock

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Batch Information

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Purity:98.50%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Trovirdine (LY300046) is a thiourea non-nucleoside reverse transcriptase inhibitor.
Targets&IC50	HIV-1 RT:7 nM
Synonyms	LY300046

Chemical Properties

Molecular Weight	337.24
Formula	C₁₃H₁₃BrN₄S
Cas No.	149488-17-5
Smiles	Brc1ccc(NC(=S)NCCc2ccccn2)nc1
Relative Density.	1.539g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (163.09 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9652 mL	14.8262 mL	29.6525 mL	148.2624 mL
5 mM	0.5930 mL	2.9652 mL	5.9305 mL	29.6525 mL
10 mM	0.2965 mL	1.4826 mL	2.9652 mL	14.8262 mL
20 mM	0.1483 mL	0.7413 mL	1.4826 mL	7.4131 mL
50 mM	0.0593 mL	0.2965 mL	0.5930 mL	2.9652 mL
100 mM	0.0297 mL	0.1483 mL	0.2965 mL	1.4826 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc