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SAHA chloroalkane T1

Name: SAHA chloroalkane T1
Brand: TargetMol
SKU: T19556
Rating: 4.5 (1 reviews)

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Catalog No. T19556Cas No. 1613617-05-2

SAHA chloroalkane T1 is a novel compound formed by combining Vorinostat (SAHA) with a chloroalkane capture tag, referred to as T1. This innovative approach involves tethering the SAHA molecule with the T1 tag, resulting in the formation of SAHA chloroalkane T1.

SAHA chloroalkane T1

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Catalog No. T19556Cas No. 1613617-05-2

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$688	6-8 weeks	6-8 weeks
50 mg	$913	6-8 weeks	6-8 weeks
100 mg	$1,530	6-8 weeks	6-8 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	SAHA chloroalkane T1 is a novel compound formed by combining Vorinostat (SAHA) with a chloroalkane capture tag, referred to as T1. This innovative approach involves tethering the SAHA molecule with the T1 tag, resulting in the formation of SAHA chloroalkane T1.
In vitro	in K-562 cells,SAHA chloroalkane T1 minimally affects SAHA potency, allowing binding interactions with the targets to occur under conditions relevant to the desired cellular phenotype.

Chemical Properties

Molecular Weight	719.26
Formula	C₃₃H₅₅ClN₄O₁₁
Cas No.	1613617-05-2
Smiles	N(C(CCCCCCC(NO)=O)=O)C1=CC=C(CNC(OCCOCCOCCOC(NCCOCCOCCCCCCCl)=O)=O)C=C1
Relative Density.	1.199 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 125 mg/mL (173.79 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Corn Oil: 3.3 mg/mL (4.59 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.3903 mL	6.9516 mL	13.9032 mL	69.5159 mL
5 mM	0.2781 mL	1.3903 mL	2.7806 mL	13.9032 mL
10 mM	0.1390 mL	0.6952 mL	1.3903 mL	6.9516 mL
20 mM	0.0695 mL	0.3476 mL	0.6952 mL	3.4758 mL
50 mM	0.0278 mL	0.1390 mL	0.2781 mL	1.3903 mL
100 mM	0.0139 mL	0.0695 mL	0.1390 mL	0.6952 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

SAHA chloroalkane T-1SAHA chloroalkane T1