Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-BMI-1 Antibody (4I124)
😃Good
Catalog No. TMAC-00455
Anti-BMI-1 Antibody (4I124) is a Rabbit antibody targeting BMI-1. Anti-BMI-1 Antibody (4I124) can be used in WB,ICC/IF,IHC.
Anti-BMI-1 Antibody (4I124)
Anti-BMI-1 Antibody (4I124)
😃Good
Catalog No. TMAC-00455
Anti-BMI-1 Antibody (4I124) is a Rabbit antibody targeting BMI-1. Anti-BMI-1 Antibody (4I124) can be used in WB,ICC/IF,IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $496 | 7-10 days |
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View MoreResource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-BMI-1 Antibody (4I124) is a Rabbit antibody targeting BMI-1. Anti-BMI-1 Antibody (4I124) can be used in WB,ICC/IF,IHC. |
| Ig Type | IgG |
| Reactivity | Human,Rat |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | In Drosophila, Polycomb (Pc-g) gene family encodes chromatin proteins that are required for the repression of homeotic loci in embryonic development. Mel-18 and Bmi-1, mammalian homologs of Drosophila Pc-g group proteins, are similarly expressed during development and implicated in the regulation of gene expression, axial skeleton development, control of proliferation and survival of haematopoietic cells. Mel-18 directly binds to DNA through a RING-finger motif and preferentially associates with juxtaposed enhancer elements on various genes, including Bcl-2, c-Myc and Hox. Mel-18 is an immediate early response gene within the c-Myc/Cdc25 signaling cascade that exhibits tumor suppressor activity and negatively regulates cell cycle progression by blocking S phase entry. Alternatively, Bmi-1 has been identified as a potent oncogene as it contributes to the transcriptional activation of genes implicated in early lymphoid development. Proviral activation of Bmi-1 expression corresponds to enhanced gene-specific activation of other proto-oncogenes, including c-Myc and Pim, subsequently resulting in the progression of lymphomagenesis. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Antigen Species | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 42 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Sci Citations
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-BMI-1 Antibody (4I124) | purchase Anti-BMI-1 Antibody (4I124) | Anti-BMI-1 Antibody (4I124) cost | order Anti-BMI-1 Antibody (4I124) | Anti-BMI-1 Antibody (4I124) molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.