Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Frunevetmab (NV-02), a felinized monoclonal antibody targeting nerve growth factor (NGF), exhibits a high affinity with a dissociation constant (Kd) of 20 pM and has been demonstrated to effectively mitigate osteoarthritis (OA) pain in cats [1] [2].
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Description | Frunevetmab (NV-02), a felinized monoclonal antibody targeting nerve growth factor (NGF), exhibits a high affinity with a dissociation constant (Kd) of 20 pM and has been demonstrated to effectively mitigate osteoarthritis (OA) pain in cats [1] [2]. |
In vitro | Frunevetmab (NV-02) neutralizes nerve growth factor (NGF) with high affinity and potency without binding to the complement system [2]. |
In vivo | Frunevetmab administered subcutaneously at a dosage of 1.0-2.8mg/kg on days 0, 28, and 56 demonstrated a positive therapeutic effect on cats with naturally occurring osteoarthritis, alleviating pain and improving associated mobility impairments and disabilities [1]. |
Synonyms | NV-02 |
Molecular Weight | N/A |
CAS No. | 1708936-80-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Frunevetmab 1708936-80-4 NV-02 NV 02 NV02 inhibitor inhibit