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Frunevetmab (Synonyms: PG-110, PG110, NV-02, NV02, ABT-110, ABT110)

Catalog No. T78316 Copy Product Info
Purity: 95%
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Frunevetmab (NV-02) is a feline-adapted monoclonal antibody targeting NGF (nerve growth factor), with a Kd value of 20 pM. This compound effectively alleviates pain associated with feline osteoarthritis (OA).

Frunevetmab

Copy Product Info
🥰Excellent
Catalog No. T78316
Synonyms PG-110, PG110, NV-02, NV02, ABT-110, ABT110

Frunevetmab (NV-02) is a feline-adapted monoclonal antibody targeting NGF (nerve growth factor), with a Kd value of 20 pM. This compound effectively alleviates pain associated with feline osteoarthritis (OA).

Frunevetmab
Cas No. 1708936-80-4
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$328-In Stock
5 mg$859-In Stock
10 mg$1,380-In Stock
25 mg$1,980-In Stock
50 mg$2,760-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:95.3% (SDS-PAGE); 98.7% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Frunevetmab (NV-02) is a feline-adapted monoclonal antibody targeting NGF (nerve growth factor), with a Kd value of 20 pM. This compound effectively alleviates pain associated with feline osteoarthritis (OA).
Targets&IC50
Felcat NGF:20 pM (Kd )
In vitro
Frunevetmab (NV-02) neutralizes nerve growth factor (NGF) with high affinity and potency without binding to the complement system [2].
In vivo
Frunevetmab administered subcutaneously at a dosage of 1.0-2.8mg/kg on days 0, 28, and 56 demonstrated a positive therapeutic effect on cats with naturally occurring osteoarthritis, alleviating pain and improving associated mobility impairments and disabilities [1].
SynonymsPG-110, PG110, NV-02, NV02, ABT-110, ABT110
Reactivity
Felcat
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
TargetNGF/bNGF
Chemical Properties
Molecular Weight147.99 kDa
Cas No.1708936-80-4
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
StorageStore at -20°C Shipping with blue ice/Shipping at ambient temperature.

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