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Frunevetmab
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Catalog No. T78316Cas No. 1708936-80-4
Alias PG-110, PG110, NV-02, NV02, ABT-110, ABT110
Frunevetmab (NV-02) is a feline-adapted monoclonal antibody targeting NGF (nerve growth factor), with a Kd value of 20 pM. This compound effectively alleviates pain associated with feline osteoarthritis (OA).
Frunevetmab
Frunevetmab
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Purity: 95%
Catalog No. T78316Alias PG-110, PG110, NV-02, NV02, ABT-110, ABT110Cas No. 1708936-80-4
Frunevetmab (NV-02) is a feline-adapted monoclonal antibody targeting NGF (nerve growth factor), with a Kd value of 20 pM. This compound effectively alleviates pain associated with feline osteoarthritis (OA).
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $328 | - | In Stock | |
| 5 mg | $859 | - | In Stock | |
| 10 mg | $1,380 | - | In Stock | |
| 25 mg | $1,980 | - | In Stock | |
| 50 mg | $2,760 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:95.3% (SDS-PAGE); 98.7% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Frunevetmab (NV-02) is a feline-adapted monoclonal antibody targeting NGF (nerve growth factor), with a Kd value of 20 pM. This compound effectively alleviates pain associated with feline osteoarthritis (OA). |
| Targets&IC50 | Felcat NGF:20 pM (Kd ) |
| In vitro | Frunevetmab (NV-02) neutralizes nerve growth factor (NGF) with high affinity and potency without binding to the complement system [2]. |
| In vivo | Frunevetmab administered subcutaneously at a dosage of 1.0-2.8mg/kg on days 0, 28, and 56 demonstrated a positive therapeutic effect on cats with naturally occurring osteoarthritis, alleviating pain and improving associated mobility impairments and disabilities [1]. |
| Synonyms | PG-110, PG110, NV-02, NV02, ABT-110, ABT110 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | NGF/bNGF |
| Molecular Weight | 147.99 kDa |
| Cas No. | 1708936-80-4 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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