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NN-390
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Catalog No. T62219Cas No. 2490284-25-6
NN-390 is a selective, potent HDAC6 inhibitor (IC50: 9.8 μM) that crosses the blood-brain barrier. nN-390 has potential for studies in metastatic group 3 neural tube cell tumours.
NN-390
😃Good
Catalog No. T62219Cas No. 2490284-25-6
NN-390 is a selective, potent HDAC6 inhibitor (IC50: 9.8 μM) that crosses the blood-brain barrier. nN-390 has potential for studies in metastatic group 3 neural tube cell tumours.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 500 μg | $198 | 35 days | 35 days | |
| 1 mg | $359 | 35 days | 35 days | |
| 5 mg | $1,430 | 35 days | 35 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Chemical Properties
| Description | NN-390 is a selective, potent HDAC6 inhibitor (IC50: 9.8 μM) that crosses the blood-brain barrier. nN-390 has potential for studies in metastatic group 3 neural tube cell tumours. |
| Targets&IC50 | HDAC1:>5 μM, HDAC6:9.8 nM, HDAC8:>1 μM, HDAC3:>1 μM, HDAC11:>1 μM, HDAC2:>5 μM |
| Molecular Weight | 420.38 |
| Formula | C17H16F4N2O4S |
| Cas No. | 2490284-25-6 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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