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N-Methylnicotinamide

Name: N-Methylnicotinamide
Brand: TargetMol
SKU: T5233
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T5233Cas No. 114-33-0

Alias N-Methylpyridine-3-carboxamide, N'-Methylnicotinamide, Nicotinic Acid Methylamide

N-Methylnicotinamide is one of the endogenous metabolites that ameliorates endothelial dysfunction.

N-Methylnicotinamide

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Purity: 99.44%

Catalog No. T5233Alias N-Methylpyridine-3-carboxamide, N'-Methylnicotinamide, Nicotinic Acid MethylamideCas No. 114-33-0

N-Methylnicotinamide is one of the endogenous metabolites that ameliorates endothelial dysfunction.

Pack Size	Price	Availability	Quantity
1 g	$35	In Stock

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Purity:99.44%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	N-Methylnicotinamide is one of the endogenous metabolites that ameliorates endothelial dysfunction.
Synonyms	N-Methylpyridine-3-carboxamide, N'-Methylnicotinamide, Nicotinic Acid Methylamide

Chemical Properties

Molecular Weight	136.15
Formula	C₇H₈N₂O
Cas No.	114-33-0
Smiles	CNC(=O)c1cccnc1
Relative Density.	1.106 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 100 mg/mL (734.4 mM), Sonication is recommended.

DMSO: 50 mg/mL (367.24 mM), Sonication is recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	7.3448 mL	36.7242 mL	73.4484 mL	367.2420 mL
5 mM	1.4690 mL	7.3448 mL	14.6897 mL	73.4484 mL
10 mM	0.7345 mL	3.6724 mL	7.3448 mL	36.7242 mL
20 mM	0.3672 mL	1.8362 mL	3.6724 mL	18.3621 mL
50 mM	0.1469 mL	0.7345 mL	1.4690 mL	7.3448 mL
100 mM	0.0734 mL	0.3672 mL	0.7345 mL	3.6724 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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