Powder: -20°C for 3 years | In solvent: -80°C for 1 year
RORγt inverse agonist 31 (14g) is a potent antagonist of the retinoic acid receptor-related orphan receptor γt (RORγt), exhibiting an inhibitory concentration (IC50) of 0.428 μM. It has demonstrated efficacy in mitigating Imiquimod-induced psoriasis severity in murine models [1].
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Description | RORγt inverse agonist 31 (14g) is a potent antagonist of the retinoic acid receptor-related orphan receptor γt (RORγt), exhibiting an inhibitory concentration (IC50) of 0.428 μM. It has demonstrated efficacy in mitigating Imiquimod-induced psoriasis severity in murine models [1]. |
Molecular Weight | 555.36 |
Formula | C23H15Cl2F3N4O3S |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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RORγt inverse agonist 31 Metabolism ROR inhibitor inhibit