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Anti-NKG2D/CD314 Antibody (6I735) is a Mouse antibody targeting NKG2D/CD314. Anti-NKG2D/CD314 Antibody (6I735) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $198 | 7-10 days |
Description | Anti-NKG2D/CD314 Antibody (6I735) is a Mouse antibody targeting NKG2D/CD314. Anti-NKG2D/CD314 Antibody (6I735) can be used in ELISA. |
Alias | NKG2-D, NKG2D, KLR, killer cell lectin-like receptor subfamily K, member 1, D12S2489E, CD314 |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 6I735 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:1000-1:2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This product is a recombinant monoclonal antibody expressed from HEK293 cells. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | KLRK1 (Killer Cell Lectin Like Receptor K1) is a Protein Coding gene. NKG2D, also known as CD314, is an immune receptor that consists of two disulfide-linked type II transmembrane proteins with short intracellular proteins incapable to transduce signals. To transduce signals, NKG2D needs adaptor proteins and it uses two adaptor proteins, DAP10 and DAP12. These two adaptor proteins associate as homodimers to NKG2D- therefore the entire receptor complex appears as a hexamer. NKG2D can send co-stimulatory signals to activate CD8 T cells. NKG2D also plays an important role in viral control. Cellular stress can induce ligands for NKG2D which results in the cell susceptible to NK cell-mediated lysis. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human NKG2D Protein (TMPY-03256) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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