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NSC 73150

🥰Excellent
Catalog No. T9398Cas No. 66680-03-3
Alias NSC 97967

6-methyl-2-[2-[(E)-(6-oxo-1-cyclohexa-2,4-dienylidene)methyl]hydraziny l]-1H-pyrimidin-4-one (NSC 73150) is a pyrimidine derivative with antitumor activity. Preclinical studies have shown that it inhibits the growth of a variety of tumor cell lines, including breast, lung, and liver cancers. It has also been found to induce apoptosis, inhibit angiogenesis and suppress tumor metastasis.

NSC 73150

NSC 73150

🥰Excellent
Purity: 99.84%
Catalog No. T9398Alias NSC 97967Cas No. 66680-03-3
6-methyl-2-[2-[(E)-(6-oxo-1-cyclohexa-2,4-dienylidene)methyl]hydraziny l]-1H-pyrimidin-4-one (NSC 73150) is a pyrimidine derivative with antitumor activity. Preclinical studies have shown that it inhibits the growth of a variety of tumor cell lines, including breast, lung, and liver cancers. It has also been found to induce apoptosis, inhibit angiogenesis and suppress tumor metastasis.
Pack SizePriceAvailabilityQuantity
1 mg$89In Stock
5 mg$202In Stock
10 mg$298In Stock
25 mg$476In Stock
50 mg$678In Stock
100 mg$912In Stock
200 mg$1,190In Stock
1 mL x 10 mM (in DMSO)$178In Stock
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Purity:99.84%
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Product Introduction

Bioactivity
Description
6-methyl-2-[2-[(E)-(6-oxo-1-cyclohexa-2,4-dienylidene)methyl]hydraziny l]-1H-pyrimidin-4-one (NSC 73150) is a pyrimidine derivative with antitumor activity. Preclinical studies have shown that it inhibits the growth of a variety of tumor cell lines, including breast, lung, and liver cancers. It has also been found to induce apoptosis, inhibit angiogenesis and suppress tumor metastasis.
SynonymsNSC 97967
Chemical Properties
Molecular Weight244.25
FormulaC12H12N4O2
Cas No.66680-03-3
SmilesCC1=CC(=O)NC(N\N=C\C2=CC=CC=C2O)=N1
Relative Density.1.34g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (225.18 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.0942 mL20.4708 mL40.9417 mL204.7083 mL
5 mM0.8188 mL4.0942 mL8.1883 mL40.9417 mL
10 mM0.4094 mL2.0471 mL4.0942 mL20.4708 mL
20 mM0.2047 mL1.0235 mL2.0471 mL10.2354 mL
50 mM0.0819 mL0.4094 mL0.8188 mL4.0942 mL
100 mM0.0409 mL0.2047 mL0.4094 mL2.0471 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

NSC-97967NSC97967NSC-73150NSC73150NSC 731506methyl2[2[(E)(6oxo1cyclohexa2,4dienylidene)methyl]hydraziny l]1Hpyrimidin4one6 methyl 2 [2 [(E) (6 oxo 1 cyclohexa 2,4 dienylidene)methyl]hydraziny l] 1H pyrimidin 4 one
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