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9H-Carbazole, 1-methyl-

Name: 9H-Carbazole, 1-methyl-
Brand: TargetMol
SKU: TN7203
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN7203Cas No. 6510-65-2

Alias 1-Methyl-carbazole, 1-Methyl-9H-carbazole, 1-methyl carbazole

9H-Carbazole, 1-methyl- (1-methyl carbazole) is a marine derived natural products found in Tedania (Tedania) ignis.

9H-Carbazole, 1-methyl-

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Purity: 99.11%

Catalog No. TN7203Alias 1-Methyl-carbazole, 1-Methyl-9H-carbazole, 1-methyl carbazoleCas No. 6510-65-2

9H-Carbazole, 1-methyl- (1-methyl carbazole) is a marine derived natural products found in Tedania (Tedania) ignis.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$30	-	In Stock
10 mg	$45	-	In Stock
25 mg	$77	-	In Stock
50 mg	$115	-	In Stock
100 mg	$172	-	In Stock
200 mg	$259	-	In Stock
1 mL x 10 mM (in DMSO)	$34	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.11%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

9H-Carbazole, 1-methyl- AI Summary

9H-Carbazole, 1-methyl- exhibits significant toxicity against brine shrimp, with a mortality rate of 82.0% after 4 hours at 25 ppm and 100.0% after 6 hours at the same concentration. It also inhibits the ATPase activity of the human C-terminally His6-tagged microtubule-activated KSP motor domain with an IC50 value of 23000.0 nM. Additionally, this compound shows cytotoxicity against human HeLa cells at 60 µM, resulting in less than 50% inhibition after 48 hours as determined by the MTT assay..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	9H-Carbazole, 1-methyl- (1-methyl carbazole) is a marine derived natural products found in Tedania (Tedania) ignis.
Synonyms	1-Methyl-carbazole, 1-Methyl-9H-carbazole, 1-methyl carbazole

Chemical Properties

Molecular Weight	181.23
Formula	C₁₃H₁₁N
Cas No.	6510-65-2
Smiles	Cc1cccc2c1[nH]c1ccccc21

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (303.48 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.5179 mL	27.5893 mL	55.1785 mL	275.8925 mL
5 mM	1.1036 mL	5.5179 mL	11.0357 mL	55.1785 mL
10 mM	0.5518 mL	2.7589 mL	5.5179 mL	27.5893 mL
20 mM	0.2759 mL	1.3795 mL	2.7589 mL	13.7946 mL
50 mM	0.1104 mL	0.5518 mL	1.1036 mL	5.5179 mL
100 mM	0.0552 mL	0.2759 mL	0.5518 mL	2.7589 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc