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Envafolimab (Synonyms: KN035, KN 035, ASC22, ASC 22)

Catalog No. T76715 Copy Product Info
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Envafolimab (ASC 22) is a humanized monoclonal antibody targeting programmed cell death ligand-1 (PD-L1), with antitumor activity. It blocks the interaction between PD-L1 and PD-1, and is used in studies of solid tumors.

Envafolimab

Copy Product Info
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Catalog No. T76715
Synonyms KN035, KN 035, ASC22, ASC 22

Envafolimab (ASC 22) is a humanized monoclonal antibody targeting programmed cell death ligand-1 (PD-L1), with antitumor activity. It blocks the interaction between PD-L1 and PD-1, and is used in studies of solid tumors.

Envafolimab
Cas No. 2102192-68-5
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$213In StockIn Stock
5 mg$562In StockIn Stock
10 mg$893-In Stock
25 mg$1,320-In Stock
50 mg$1,780-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.31% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Envafolimab (ASC 22) is a humanized monoclonal antibody targeting programmed cell death ligand-1 (PD-L1), with antitumor activity. It blocks the interaction between PD-L1 and PD-1, and is used in studies of solid tumors.
In vitro
Envafolimab can inhibit the growth of gastric cancer cells with low PD-L1 expression by down-regulating DDX20 expression and regulating NFκB/TNF-α signaling pathway. [1]
SynonymsKN035, KN 035, ASC22, ASC 22
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetB7-H1/PD-L1/CD274
Chemical Properties
Molecular Weight80 kDa
Cas No.2102192-68-5
Antibody Information
IsotypeHuman IgG1
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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