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Anti-TNF beta Antibody (7E588)

😃Good
Catalog No. TMAY-00542
Alias TNFSF1, TNFB, TNF β, lymphotoxin α, lymphotoxin alpha, LT

Anti-TNF beta Antibody (7E588) is a Rabbit antibody targeting TNF beta. Anti-TNF beta Antibody (7E588) can be used in ELISA(Det).

Anti-TNF beta Antibody (7E588)

Anti-TNF beta Antibody (7E588)

😃Good
Catalog No. TMAY-00542Alias TNFSF1, TNFB, TNF β, lymphotoxin α, lymphotoxin alpha, LT
Anti-TNF beta Antibody (7E588) is a Rabbit antibody targeting TNF beta. Anti-TNF beta Antibody (7E588) can be used in ELISA(Det).
Pack SizePriceAvailabilityQuantity
20 μL$94 7-10 days
100 μL$293 7-10 days
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Product Introduction

Bioactivity
Description
Anti-TNF beta Antibody (7E588) is a Rabbit antibody targeting TNF beta. Anti-TNF beta Antibody (7E588) can be used in ELISA(Det).
AliasTNFSF1, TNFB, TNF β, lymphotoxin α, lymphotoxin alpha, LT
Ig Type
Monoclonal Rabbit IgG
Clone
7E588
Reactivity
Human
Application
ELISA(Det)
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human TNF-beta / TNFSF1 / Lymphotoxin alpha (rh TNF-beta / TNFSF1 / Lymphotoxin alpha ; TMPY-02153; P01374; Leu35-Leu205).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundLymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lymphotoxin alpha is highly inducible, secreted, and exists as a homotrimeric molecule. It is a cytokine that in its homotrimeric form binds to TNFRSF1A / TNFR1, TNFRSF1B / TNFBR, and TNFRSF14 / HVEM. In its heterotrimeric form with LTB, TNF-beta/TNFSF1/Lymphotoxin alpha binds to TNFRSF3 / LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells. TNF-beta/TNFSF1/Lymphotoxin alpha forms heterotrimers with lymphotoxin-beta which anchors lymphotoxin-alpha to the cell surface. It mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. TNF-beta/TNFSF1/Lymphotoxin alpha is also involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in TNF-beta/TNFSF1/Lymphotoxin alpha are a cause of susceptibility psoriatic arthritis which is an inflammatory, seronegative arthritis associated with psoriasis. It is a heterogeneous disorder ranging from a mild, non-destructive disease to a severe, progressive, erosive arthropathy.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
HRP
Antibody Types Available
2
Antigen Details
Immunogen
Recombinant Human TNF-beta / TNFSF1 / Lymphotoxin alpha protein (TMPY-02153)
Antigen Species
Human
Biology Area
Neuroinflammation
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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