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Anti-TNF beta Antibody (7E588) (Alias: TNFSF1, TNFB, TNF β, lymphotoxin α, lymphotoxin alpha, LT)

Catalog No. TMAY-00542 Copy Product Info
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Anti-TNF beta Antibody (7E588) is a Rabbit antibody targeting TNF beta. Anti-TNF beta Antibody (7E588) can be used in ELISA(Det).

Anti-TNF beta Antibody (7E588)

Copy Product Info
🥰Excellent
Catalog No. TMAY-00542
Alias TNFSF1, TNFB, TNF β, lymphotoxin α, lymphotoxin alpha, LT

Anti-TNF beta Antibody (7E588) is a Rabbit antibody targeting TNF beta. Anti-TNF beta Antibody (7E588) can be used in ELISA(Det).

Anti-TNF beta Antibody
(7E588)
Pack SizePriceUSA StockGlobal StockQuantity
20 μL$947-10 days7-10 days
100 μL$2937-10 days7-10 days
In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-TNF beta Antibody (7E588) is a Rabbit antibody targeting TNF beta. Anti-TNF beta Antibody (7E588) can be used in ELISA(Det).
SynonymsTNFSF1, TNFB, TNF β, lymphotoxin α, lymphotoxin alpha, LT
Ig Type
Rabbit IgG
Clone
7E588
Reactivity
Human
Specificity
Human Lymphotoxin alpha/TNF beta
No cross-reactivity in ELISA with
Human TNFa
Mouse TNFa
Human TNFRII
Application
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human TNF-beta / TNFSF1 / Lymphotoxin alpha (rh TNF-beta / TNFSF1 / Lymphotoxin alpha ; TMPY-02153; P01374; Leu35-Leu205).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundLymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lymphotoxin alpha is highly inducible, secreted, and exists as a homotrimeric molecule. It is a cytokine that in its homotrimeric form binds to TNFRSF1A / TNFR1, TNFRSF1B / TNFBR, and TNFRSF14 / HVEM. In its heterotrimeric form with LTB, TNF-beta/TNFSF1/Lymphotoxin alpha binds to TNFRSF3 / LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells. TNF-beta/TNFSF1/Lymphotoxin alpha forms heterotrimers with lymphotoxin-beta which anchors lymphotoxin-alpha to the cell surface. It mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. TNF-beta/TNFSF1/Lymphotoxin alpha is also involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in TNF-beta/TNFSF1/Lymphotoxin alpha are a cause of susceptibility psoriatic arthritis which is an inflammatory, seronegative arthritis associated with psoriasis. It is a heterogeneous disorder ranging from a mild, non-destructive disease to a severe, progressive, erosive arthropathy.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
HRP
Antibody Types Available
2
Antigen Details
Immunogen
Recombinant Protein: Human TNF-beta / TNFSF1 / Lymphotoxin alpha protein (TMPY-02153)
Antigen Species
Human
Biology Area
Neuroinflammation
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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