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Anti-TNF beta Antibody (7E588) is a Rabbit antibody targeting TNF beta. Anti-TNF beta Antibody (7E588) can be used in ELISA(Det).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
20 μL | $94 | 7-10 days | |
100 μL | $293 | 7-10 days |
Description | Anti-TNF beta Antibody (7E588) is a Rabbit antibody targeting TNF beta. Anti-TNF beta Antibody (7E588) can be used in ELISA(Det). |
Alias | TNFSF1, TNFB, TNF β, lymphotoxin α, lymphotoxin alpha, LT |
Ig Type | Monoclonal Rabbit IgG |
Clone | 7E588 |
Reactivity | Human |
Application | ELISA(Det) |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human TNF-beta / TNFSF1 / Lymphotoxin alpha (rh TNF-beta / TNFSF1 / Lymphotoxin alpha ; TMPY-02153; P01374; Leu35-Leu205). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lymphotoxin alpha is highly inducible, secreted, and exists as a homotrimeric molecule. It is a cytokine that in its homotrimeric form binds to TNFRSF1A / TNFR1, TNFRSF1B / TNFBR, and TNFRSF14 / HVEM. In its heterotrimeric form with LTB, TNF-beta/TNFSF1/Lymphotoxin alpha binds to TNFRSF3 / LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells. TNF-beta/TNFSF1/Lymphotoxin alpha forms heterotrimers with lymphotoxin-beta which anchors lymphotoxin-alpha to the cell surface. It mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. TNF-beta/TNFSF1/Lymphotoxin alpha is also involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in TNF-beta/TNFSF1/Lymphotoxin alpha are a cause of susceptibility psoriatic arthritis which is an inflammatory, seronegative arthritis associated with psoriasis. It is a heterogeneous disorder ranging from a mild, non-destructive disease to a severe, progressive, erosive arthropathy. |
Conjucates | Unconjugated |
Others Formats | HRP |
Antibody Types Available | 2 |
Immunogen | Recombinant Human TNF-beta / TNFSF1 / Lymphotoxin alpha protein (TMPY-02153) |
Antigen Species | Human |
Biology Area | Neuroinflammation |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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