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EIF2α activator 2

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Catalog No. T62637Cas No. 1501618-04-7

EIF2α activator 2 (Compound 1) is an activator of eIF2α phosphorylation, exhibiting anti-proliferative activity at the μM level in SRB, K562, and PBMC cells, suitable for cancer research.

EIF2α activator 2

EIF2α activator 2

😃Good
Purity: 98.86%
Catalog No. T62637Cas No. 1501618-04-7
EIF2α activator 2 (Compound 1) is an activator of eIF2α phosphorylation, exhibiting anti-proliferative activity at the μM level in SRB, K562, and PBMC cells, suitable for cancer research.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$52-In Stock
5 mg$123-In Stock
10 mg$197-In Stock
25 mg$369-In Stock
50 mg$549-In Stock
100 mg$789-In Stock
200 mg$1,080-In Stock
1 mL x 10 mM (in DMSO)$135-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:98.86%
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Product Introduction

Bioactivity
Description
EIF2α activator 2 (Compound 1) is an activator of eIF2α phosphorylation, exhibiting anti-proliferative activity at the μM level in SRB, K562, and PBMC cells, suitable for cancer research.
Chemical Properties
Molecular Weight446.39
FormulaC21H20F6N2O2
Cas No.1501618-04-7
SmilesN(C(N[C@H]1CC[C@H](OC2=CC=C(C(F)(F)F)C=C2)CC1)=O)C3=CC(C(F)(F)F)=CC=C3
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 200 mg/mL (448.04 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2402 mL11.2010 mL22.4019 mL112.0097 mL
5 mM0.4480 mL2.2402 mL4.4804 mL22.4019 mL
10 mM0.2240 mL1.1201 mL2.2402 mL11.2010 mL
20 mM0.1120 mL0.5600 mL1.1201 mL5.6005 mL
50 mM0.0448 mL0.2240 mL0.4480 mL2.2402 mL
100 mM0.0224 mL0.1120 mL0.2240 mL1.1201 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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