Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MS143, a potent AKT degrader (DC50=46 nM and GI50=0.8 µM in PC3 cells), effectively induces AKT degradation through the ubiquitin-proteasome system in both a concentration- and time-dependent manner, leading to the suppression of cancer cell growth [1].
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Description | MS143, a potent AKT degrader (DC50=46 nM and GI50=0.8 µM in PC3 cells), effectively induces AKT degradation through the ubiquitin-proteasome system in both a concentration- and time-dependent manner, leading to the suppression of cancer cell growth [1]. |
Molecular Weight | 1121.87 |
Formula | C59H81ClN12O6S |
CAS No. | 2376137-41-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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MS143 2376137-41-4 inhibitor inhibit