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Alisol A 24-acetate

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Catalog No. T6S2243Cas No. 18674-16-3
Alias Alisol A monoacetate, Alisol A 24-monoacetate

1. Alisol A 24-acetate (Alisol A monoacetate) has been determined for the quality control of this crude drug.

Alisol A 24-acetate

Alisol A 24-acetate

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Purity: 98.75%
Catalog No. T6S2243Alias Alisol A monoacetate, Alisol A 24-monoacetateCas No. 18674-16-3
1. Alisol A 24-acetate (Alisol A monoacetate) has been determined for the quality control of this crude drug.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$36In StockIn Stock
5 mg$77In StockIn Stock
10 mg$108In StockIn Stock
25 mg$179In StockIn Stock
50 mg$266In StockIn Stock
100 mg$395-In Stock
200 mg$588-In Stock
1 mL x 10 mM (in DMSO)$95In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:98.75%
Appearance:Solid
Color:White
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Product Introduction

Alisol A 24-acetate AI Summary
Alisol A 24-acetate exhibits antiviral activity against Hepatitis B virus in human HepG2.2.15 cells by decreasing HBV surface antigen secretion, with an IC50 value of 600.0 nM. It also demonstrates good plasma protein binding in rats, with values ranging from 70.01% to 72.1%, indicating that a significant portion of the compound remains bound to plasma proteins in the bloodstream. Additionally, the compound shows bioactivity in transactivating FXR in HepG2 cells co-expressing pBSEP/pGL4.74, with an EC50 value of 34190.0 nM as determined by a luciferase reporter gene assay..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
1. Alisol A 24-acetate (Alisol A monoacetate) has been determined for the quality control of this crude drug.
SynonymsAlisol A monoacetate, Alisol A 24-monoacetate
Chemical Properties
Molecular Weight532.75
FormulaC32H52O6
Cas No.18674-16-3
SmilesC[C@H](C[C@H](O)[C@@H](OC(C)=O)C(C)(C)O)C1=C2C[C@H](O)[C@H]3[C@@]4(C)CCC(=O)C(C)(C)[C@@H]4CC[C@]3(C)[C@@]2(C)CC1
Relative Density.1.14 g/cm3
Storage & Solubility Information
StorageIn solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (93.85 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.8771 mL9.3853 mL18.7705 mL93.8527 mL
5 mM0.3754 mL1.8771 mL3.7541 mL18.7705 mL
10 mM0.1877 mL0.9385 mL1.8771 mL9.3853 mL
20 mM0.0939 mL0.4693 mL0.9385 mL4.6926 mL
50 mM0.0375 mL0.1877 mL0.3754 mL1.8771 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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