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Anti-GDF-15 Antibody (9V616) (Synonyms: PTGFB, PLAB, PDF, NAG-1, MIC-1, MIC1, growth differentiation facto...)

Catalog No. TMAY-01353 Copy Product Info
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Anti-GDF-15 Antibody (9V616) is a Mouse antibody targeting GDF-15. Anti-GDF-15 Antibody (9V616) can be used in ELISA.

Anti-GDF-15 Antibody (9V616)

Copy Product Info
🥰Excellent
Catalog No. TMAY-01353
Synonyms PTGFB, PLAB, PDF, NAG-1, MIC-1, MIC1, growth differentiation factor 15, GDF-15

Anti-GDF-15 Antibody (9V616) is a Mouse antibody targeting GDF-15. Anti-GDF-15 Antibody (9V616) can be used in ELISA.

Anti-GDF-15 Antibody
(9V616)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$1997-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-GDF-15 Antibody (9V616) is a Mouse antibody targeting GDF-15. Anti-GDF-15 Antibody (9V616) can be used in ELISA.
SynonymsPTGFB, PLAB, PDF, NAG-1, MIC-1, MIC1, growth differentiation factor 15, GDF-15
Ig Type
Mouse IgG1
Clone
9V616
Reactivity
Human
Specificity
Human GDF-15
Application
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GDF15 (rh GDF15; TMPY-04727; NP_004855.2; Ala197-Ile308). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundGrowth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 / GDF15 is not expressed in the normal adult heart but is induced in response to conditions that promote hypertrophy and dilated cardiomyopathy and it is expressed highly in liver. GDF-15 / GDF15 has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. GDF-15 / GDF15 is synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein. GDF-15 / GDF15 overexpression arising from an expanded erythroid compartment contributes to iron overload in thalassemia syndromes by inhibiting hepcidin expression.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human GDF15 Protein (TMPY-04727)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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