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Anti-TAL-1 Antibody (7H409)
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Catalog No. TMAC-03961
Alias TCL5, TCL 5, T-cell leukemia/lymphoma protein 5, T-cell acute lymphocytic leukemia protein 1, TAL1_HUMAN, tal1, TAL 1 protein, Tal 1 product, Tal 1, T cell leukemia/lymphoma 5 protein, T cell acute lymphocytic leukemia 1 protein, T cell acute lymphocytic leukemia 1, Stem cell protein, STEM CELL LEUKEMIA HEMATOPOIETIC TRANSCRIPTION FACTOR, SCL, OTTHUMP00000009564, OTTHUMP00000009563, Class A basic helix-loop-helix protein 17, bHLHa17
Anti-TAL-1 Antibody (7H409) is a Mouse antibody targeting TAL-1. Anti-TAL-1 Antibody (7H409) can be used in IF,IP,WB.
Anti-TAL-1 Antibody (7H409)
Anti-TAL-1 Antibody (7H409)
😃Good
Catalog No. TMAC-03961Alias TCL5, TCL 5, T-cell leukemia/lymphoma protein 5, T-cell acute lymphocytic leukemia protein 1, TAL1_HUMAN, tal1, TAL 1 protein, Tal 1 product, Tal 1, T cell leukemia/lymphoma 5 protein, T cell acute lymphocytic leukemia 1 protein, T cell acute lymphocytic leukemia 1, Stem cell protein, STEM CELL LEUKEMIA HEMATOPOIETIC TRANSCRIPTION FACTOR, SCL, OTTHUMP00000009564, OTTHUMP00000009563, Class A basic helix-loop-helix protein 17, bHLHa17
Anti-TAL-1 Antibody (7H409) is a Mouse antibody targeting TAL-1. Anti-TAL-1 Antibody (7H409) can be used in IF,IP,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $298 | 7-10 days | 7-10 days | |
| 100 μL | $427 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-TAL-1 Antibody (7H409) is a Mouse antibody targeting TAL-1. Anti-TAL-1 Antibody (7H409) can be used in IF,IP,WB. |
| Synonyms | TCL5, TCL 5, T-cell leukemia/lymphoma protein 5, T-cell acute lymphocytic leukemia protein 1, TAL1_HUMAN, tal1, TAL 1 protein, Tal 1 product, Tal 1, T cell leukemia/lymphoma 5 protein, T cell acute lymphocytic leukemia 1 protein, T cell acute lymphocytic leukemia 1, Stem cell protein, STEM CELL LEUKEMIA HEMATOPOIETIC TRANSCRIPTION FACTOR, SCL, OTTHUMP00000009564, OTTHUMP00000009563, Class A basic helix-loop-helix protein 17, bHLHa17 |
| Clone | 7H409 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of TAL1 expression in non-transfected (A) and human TAL1 transfected (B) 293T whole cell lysates and CCRF-CEM (C), Jurkat (D) and K-562 (E) nuclear extracts.  |
| Application | |
| Recommended Dose | WB: 1:100-1000; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Activation of TAL1 characterizes up to 60% of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition, leukemogenesis is accelerated dramatically by transgenic coexpression of TAL1 and the catalytic subunit of casein kinase IIα, a serine/ threonine protein kinase known to modulate the activity of other βHLH transcription factors. |
| Conjucates | Unconjugated |
| Immunogen | Peptide |
| Uniprot ID |
| Molecular Weight | Theoretical: 42 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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