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Cassiaside

Name: Cassiaside
Brand: TargetMol
SKU: TN1472
Price: 615 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. TN1472Cas No. 13709-03-0

Cassiaside is a naphthyl ketone glycoside that inhibits BACE1 (IC50= 4.45 μM; Ki=9.85 μM).Cassiaside exhibits significant hepatoprotective effects against galactosamine injury and has potential anti-Alzheimer's disease (AD) activity.

Cassiaside

🥰Excellent

Purity: 99.89%

Catalog No. TN1472Cas No. 13709-03-0

Pack Size	Price	Availability
1 mg	$84	In Stock
5 mg	$213	In Stock
10 mg	$369	In Stock
25 mg	$615	In Stock
50 mg	Preferential	In Stock

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Batch Information

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Purity:99.89%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Cassiaside is a naphthyl ketone glycoside that inhibits BACE1 (IC50= 4.45 μM; Ki=9.85 μM).Cassiaside exhibits significant hepatoprotective effects against galactosamine injury and has potential anti-Alzheimer's disease (AD) activity.
Targets&IC50	BACE1:4.45 μM, BACE1:9.85 μM(Ki)

Chemical Properties

Molecular Weight	420.37
Formula	C₂₀H₂₀O₁₀
Cas No.	13709-03-0
Smiles	O(C=1C2=C(C=C3C(=C2O)C(=O)C=C(C)O3)C=C(O)C1)[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O
Relative Density.	1.660 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 20 mg/mL (47.57 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3789 mL	11.8943 mL	23.7886 mL	118.9428 mL
5 mM	0.4758 mL	2.3789 mL	4.7577 mL	23.7886 mL
10 mM	0.2379 mL	1.1894 mL	2.3789 mL	11.8943 mL
20 mM	0.1189 mL	0.5947 mL	1.1894 mL	5.9471 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc