Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density.[1] This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production.[2] Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). AHLs vary in acyl group length (C4-C18), in the substitution of C3 (hydrogen, hydroxyl, or oxo group) and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family.[3] C16:1-Δ9-(L)-HSL is a long-chain AHL that functions as a quorum sensing signaling molecule in strains of S. meliloti.[4],[5],[6],[7] Regulating bacterial quorum sensing signaling can be used to inhibit pathogenesis and thus, represents a new approach to antimicrobial therapy in the treatment of infectious diseases.[8]
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 35 days | $ 110.00 | |
10 mg | 35 days | $ 210.00 | |
25 mg | 35 days | $ 483.00 | |
50 mg | 35 days | $ 853.00 |
Description | Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density.[1] This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production.[2] Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). AHLs vary in acyl group length (C4-C18), in the substitution of C3 (hydrogen, hydroxyl, or oxo group) and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family.[3] C16:1-Δ9-(L)-HSL is a long-chain AHL that functions as a quorum sensing signaling molecule in strains of S. meliloti.[4],[5],[6],[7] Regulating bacterial quorum sensing signaling can be used to inhibit pathogenesis and thus, represents a new approach to antimicrobial therapy in the treatment of infectious diseases.[8] |
Synonyms | N-(2-oxotetrahydrofuran-3S-yl) Palmitoleyl Amide, N-cis-hexadec-9Z-enoyl-L-Homoserine lactone |
Molecular Weight | 337.504 |
Formula | C20H35NO3 |
CAS No. | 479050-94-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMF: 20 mg/mL
DMSO: 20 mg/mL
You can also refer to dose conversion for different animals. More
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N-cis-hexadec-9Z-enoyl-L-Homoserine lactone 479050-94-7 Ncishexadec9ZenoylLHomoserine lactone N-(2-oxotetrahydrofuran-3S-yl) Palmitoleyl Amide N cis hexadec 9Z enoyl L Homoserine lactone inhibitor inhibit