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Z26395438

Name: Z26395438
Brand: TargetMol
SKU: T77653
Price: 52 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T77653Cas No. 2803-63-6

Z26395438 is an inhibitor of Sirtuin-1 with IC50 of 1.6 μM.

Z26395438

🥰Excellent

Purity: 99.63%

Catalog No. T77653Cas No. 2803-63-6

Z26395438 is an inhibitor of Sirtuin-1 with IC50 of 1.6 μM.

Pack Size	Price	Availability
1 mg	$52	In Stock
2 mg	$74	In Stock
5 mg	$123	In Stock
10 mg	$189	In Stock
25 mg	$347	In Stock
50 mg	$496	In Stock
100 mg	$737	In Stock
500 mg	$1,480	In Stock

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Batch Information

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Purity:99.63%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description

Z26395438 is an inhibitor of Sirtuin-1 with IC50 of 1.6 μM.

Chemical Properties

Molecular Weight	282.31
Formula	C₁₇H₁₅FN₂O
Cas No.	2803-63-6
Smiles	C(CNC(=O)C1=CC=C(F)C=C1)C=2C=3C(NC2)=CC=CC3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (159.4 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5422 mL	17.7110 mL	35.4221 mL	177.1103 mL
5 mM	0.7084 mL	3.5422 mL	7.0844 mL	35.4221 mL
10 mM	0.3542 mL	1.7711 mL	3.5422 mL	17.7110 mL
20 mM	0.1771 mL	0.8856 mL	1.7711 mL	8.8555 mL
50 mM	0.0708 mL	0.3542 mL	0.7084 mL	3.5422 mL
100 mM	0.0354 mL	0.1771 mL	0.3542 mL	1.7711 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc