Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Tosatoxumab (AR-301; KBSA301), a human immunoglobulin G1 monoclonal antibody, specifically targets and neutralizes S. aureus alpha-toxin (alpha-hemolysin; Hla) by binding to its N-terminal epitope. This interaction blocks the toxin's ability to form functional pore oligomers, crucial for its pathogenic activity. As a result, Tosatoxumab offers promising potential as an adjunctive passive immunotherapy alongside conventional antibiotics for S. aureus pneumonia [1] [2].
Pack Size | Availability | Price/USD | Quantity |
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5 mg | Inquiry | Inquiry |
Description | Tosatoxumab (AR-301; KBSA301), a human immunoglobulin G1 monoclonal antibody, specifically targets and neutralizes S. aureus alpha-toxin (alpha-hemolysin; Hla) by binding to its N-terminal epitope. This interaction blocks the toxin's ability to form functional pore oligomers, crucial for its pathogenic activity. As a result, Tosatoxumab offers promising potential as an adjunctive passive immunotherapy alongside conventional antibiotics for S. aureus pneumonia [1] [2]. |
Molecular Weight | N/A |
CAS No. | 1374419-41-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Tosatoxumab 1374419-41-6 inhibitor inhibit