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Anti-DKK1 Antibody (4W115)

😃Good
Catalog No. TMAY-00396
Alias dickkopf WNT signaling pathway inhibitor 1

Anti-DKK1 Antibody (4W115) is a Mouse antibody targeting DKK1. Anti-DKK1 Antibody (4W115) can be used in ELISA(Cap).

Anti-DKK1 Antibody (4W115)

Anti-DKK1 Antibody (4W115)

😃Good
Catalog No. TMAY-00396Alias dickkopf WNT signaling pathway inhibitor 1
Anti-DKK1 Antibody (4W115) is a Mouse antibody targeting DKK1. Anti-DKK1 Antibody (4W115) can be used in ELISA(Cap).
Pack SizePriceAvailabilityQuantity
20 μL$69 7-10 days
100 μL$199 7-10 days
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Product Introduction

Bioactivity
Description
Anti-DKK1 Antibody (4W115) is a Mouse antibody targeting DKK1. Anti-DKK1 Antibody (4W115) can be used in ELISA(Cap).
Aliasdickkopf WNT signaling pathway inhibitor 1
Ig Type
Monoclonal Mouse IgG1
Clone
4W115
Reactivity
Human
Application
ELISA(Cap)
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human DKK1 / Dkk-1 (rh DKK1 / Dkk-1; TMPY-00775; NP_036374.1; Met2-His266). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundDickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 and promote the internalization of LRP5/6. Dickkopf related protein 1 (DKK-1) was initially identified as an inducer of head formation in Xenopus embryos. DKK-1 protein modulates Wnt signaling pathway during embryonic development. Increased levels of DKK-1 are found in the majority of lung cancers, esophageal squamous cell carcinomas, and hormone-resistant breast cancers, while DKK-1 expression is decreased in malignant melanoma and colorectal cancers.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human DKK1 / Dkk-1 Protein (TMPY-00775)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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