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Anti-DKK1 Antibody (4W115)
😃Good
Catalog No. TMAY-00396
Alias dickkopf WNT signaling pathway inhibitor 1
Anti-DKK1 Antibody (4W115) is a Mouse antibody targeting DKK1. Anti-DKK1 Antibody (4W115) can be used in ELISA(Cap).
Anti-DKK1 Antibody (4W115)
Anti-DKK1 Antibody (4W115)
😃Good
Catalog No. TMAY-00396Alias dickkopf WNT signaling pathway inhibitor 1
Anti-DKK1 Antibody (4W115) is a Mouse antibody targeting DKK1. Anti-DKK1 Antibody (4W115) can be used in ELISA(Cap).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $69 | 7-10 days | |
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA(Cap) Reactivity: Human |
| Alias | dickkopf WNT signaling pathway inhibitor 1 |
| Ig Type | Mouse IgG1 |
| Clone | 4W115 |
| Reactivity | Human |
| Application | ELISA(Cap) |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human DKK1 / Dkk-1 (rh DKK1 / Dkk-1; TMPY-00775; NP_036374.1; Met2-His266). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 and promote the internalization of LRP5/6. Dickkopf related protein 1 (DKK-1) was initially identified as an inducer of head formation in Xenopus embryos. DKK-1 protein modulates Wnt signaling pathway during embryonic development. Increased levels of DKK-1 are found in the majority of lung cancers, esophageal squamous cell carcinomas, and hormone-resistant breast cancers, while DKK-1 expression is decreased in malignant melanoma and colorectal cancers. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human DKK1 / Dkk-1 Protein (TMPY-00775) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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