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Tacalcitol

🥰Excellent
Catalog No. T13912Cas No. 57333-96-7
Alias 1.alpha.,24R-Dihydroxyvitamin D3, 1,24(R)-Dihydroxyvitamin D3

Tacalcitol (1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) promotes normal bone development by regulating calcium and modulates immunological and inflammatory processes.

Tacalcitol
Other Forms of Tacalcitol:
Tacalcitol monohydrateT1391193129-94-3
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Tacalcitol

🥰Excellent
Catalog No. T13912Alias 1.alpha.,24R-Dihydroxyvitamin D3, 1,24(R)-Dihydroxyvitamin D3Cas No. 57333-96-7
Tacalcitol (1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) promotes normal bone development by regulating calcium and modulates immunological and inflammatory processes.
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Product Introduction

Bioactivity
Description
Tacalcitol (1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) promotes normal bone development by regulating calcium and modulates immunological and inflammatory processes.
Kinase Assay
6. Matsumoto K, Hashimoto K, Kiyoki M, Yamamoto M, Yoshikawa K.Effect of 1,24R-dihydroxyvitamin D3 on the growth of human keratinocytes.J Dermatol. 1990 Feb;17(2):97-103.
Cell Research
http://www.ncbi.nlm.nih.gov/pubmed/2158504
Synonyms1.alpha.,24R-Dihydroxyvitamin D3, 1,24(R)-Dihydroxyvitamin D3
Chemical Properties
Molecular Weight416.64
FormulaC27H44O3
Cas No.57333-96-7
Relative Density.1.06 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 100 mg/mL (240.02 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween-80+45% Saline: 3.3 mg/mL (7.92 mM), Sonication is recommeded.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4002 mL12.0008 mL24.0015 mL120.0077 mL
5 mM0.4800 mL2.4002 mL4.8003 mL24.0015 mL
10 mM0.2400 mL1.2001 mL2.4002 mL12.0008 mL
20 mM0.1200 mL0.6000 mL1.2001 mL6.0004 mL
50 mM0.0480 mL0.2400 mL0.4800 mL2.4002 mL
100 mM0.0240 mL0.1200 mL0.2400 mL1.2001 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Tacalcitol1,24Dihydroxyvitamin D3
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