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Avdoralimab
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Catalog No. T76913Cas No. 2226393-85-5
Alias IPH5401, IPH 5401, Anti-C5aR1 mAb
Avdoralimab (IPH 5401) is a humanized monoclonal antibody targeting Complement C5a receptor 1 (C5aR1), used in research on bullous pemphigoid and chronic urticaria.
Avdoralimab
Avdoralimab
😃Good
Catalog No. T76913Alias IPH5401, IPH 5401, Anti-C5aR1 mAbCas No. 2226393-85-5
Avdoralimab (IPH 5401) is a humanized monoclonal antibody targeting Complement C5a receptor 1 (C5aR1), used in research on bullous pemphigoid and chronic urticaria.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $263 | In Stock | In Stock | |
| 5 mg | $795 | In Stock | In Stock | |
| 10 mg | $1,260 | - | In Stock | |
| 25 mg | $1,870 | - | In Stock | |
| 50 mg | $2,520 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:95.16% (SEC-HPLC)
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| Description | Avdoralimab (IPH 5401) is a humanized monoclonal antibody targeting Complement C5a receptor 1 (C5aR1), used in research on bullous pemphigoid and chronic urticaria. |
| In vitro | Avdoralimab is a whole-human IgG κb monoclonal antibody that targets the complement C5a receptor 1 (C5aR1), preventing it from binding to C5a. Improving the role of complement cascade in tumor biology by reducing the migration and activation of neutrophils and myeloid suppressor cells to the tumor microenvironment, and enhancing the antitumor activity of effector cells such as T cells and natural killer cells. [1] |
| In vivo | Avdoralimab blocked C5A-mediated recruitment and activation of human bone marrow cells and inhibited acute lung injury in human C5aR1 knockin mice. [2] |
| Synonyms | IPH5401, IPH 5401, Anti-C5aR1 mAb |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | Complement C5aR1 |
| Molecular Weight | 145.9 kDa |
| Cas No. | 2226393-85-5 |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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