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Thiazole orange dimer YOYO 1

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Catalog No. T87518Cas No. 143413-85-8
Alias YOYO1, YOYO 1

Thiazole orange dimer YOYO-1 is a green fluorescent dye used for DNA staining. It is a tetracationic homodimer of oxazole yellow (YO) and is typically provided as a tetraiodide salt. In aqueous buffer, the free YOYO-1 dye (λmax 458 nm; λmax 564 nm) exhibits low fluorescence quantum yield, but upon binding to double-stranded DNA through diintercalation, its fluorescence intensity increases by 3200 times (λmax 489 nm; λmax 509 nm).

Thiazole orange dimer YOYO 1

Thiazole orange dimer YOYO 1

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Catalog No. T87518Alias YOYO1, YOYO 1Cas No. 143413-85-8
Thiazole orange dimer YOYO-1 is a green fluorescent dye used for DNA staining. It is a tetracationic homodimer of oxazole yellow (YO) and is typically provided as a tetraiodide salt. In aqueous buffer, the free YOYO-1 dye (λmax 458 nm; λmax 564 nm) exhibits low fluorescence quantum yield, but upon binding to double-stranded DNA through diintercalation, its fluorescence intensity increases by 3200 times (λmax 489 nm; λmax 509 nm).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$1,5206-8 weeks6-8 weeks
50 mg$1,9806-8 weeks6-8 weeks
100 mg$2,5006-8 weeks6-8 weeks
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Thiazole orange dimer YOYO-1 is a green fluorescent dye used for DNA staining. It is a tetracationic homodimer of oxazole yellow (YO) and is typically provided as a tetraiodide salt. In aqueous buffer, the free YOYO-1 dye (λmax 458 nm; λmax 564 nm) exhibits low fluorescence quantum yield, but upon binding to double-stranded DNA through diintercalation, its fluorescence intensity increases by 3200 times (λmax 489 nm; λmax 509 nm).
SynonymsYOYO1, YOYO 1
Chemical Properties
Molecular Weight1270.64
FormulaC49H58I4N6O2
Cas No.143413-85-8
SmilesCN(C1=CC=CC=C1O/2)C2=C/C3=CC=[N+](C4=C3C=CC=C4)CCC[N+](C)(C)CCC[N+](C)(C)CCC[N+]5=CC=C(C6=C5C=CC=C6)/C=C7N(C8=CC=CC=C8O\7)C.[I-].[I-].[I-].[I-]
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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